Chirkin E - Search Results

1

2-Guanidino-quinazoline promotes the readthrough of nonsense mutations underlying human genetic diseases.

Bidou L, Bugaud O, Merer G, Coupet M, Hatin I, Chirkin E, Karri S, Demais S, François P, Cintrat JC, Namy O. Bidou L, et al. Among authors: chirkin e. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2122004119. doi: 10.1073/pnas.2122004119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994666 Free PMC article.

2

Photochemical Strain-Release-Driven Cyclobutylation of C(sp³ )-Centered Radicals.

Ernouf G, Chirkin E, Rhyman L, Ramasami P, Cintrat JC. Ernouf G, et al. Among authors: chirkin e. Angew Chem Int Ed Engl. 2020 Feb 10;59(7):2618-2622. doi: 10.1002/anie.201908951. Epub 2019 Nov 6. Angew Chem Int Ed Engl. 2020. PMID: 31599038

3

Neutralization of Pathogenic Fungi with Small-Molecule Immunotherapeutics.

Chirkin E, Muthusamy V, Mann P, Roemer T, Nantermet PG, Spiegel DA. Chirkin E, et al. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13036-13040. doi: 10.1002/anie.201707536. Epub 2017 Sep 11. Angew Chem Int Ed Engl. 2017. PMID: 28793176

4

Bifunctional small molecules that mediate the degradation of extracellular proteins.

Caianiello DF, Zhang M, Ray JD, Howell RA, Swartzel JC, Branham EMJ, Chirkin E, Sabbasani VR, Gong AZ, McDonald DM, Muthusamy V, Spiegel DA. Caianiello DF, et al. Among authors: chirkin e. Nat Chem Biol. 2021 Sep;17(9):947-953. doi: 10.1038/s41589-021-00851-1. Epub 2021 Aug 19. Nat Chem Biol. 2021. PMID: 34413525

5

Effect of Probiotic Bacteria on the Gut Microbiome of Mice with Lipopolysaccharide-Induced Inflammation.

Gryaznova M, Burakova I, Smirnova Y, Morozova P, Chirkin E, Gureev A, Mikhaylov E, Korneeva O, Syromyatnikov M. Gryaznova M, et al. Among authors: chirkin e. Microorganisms. 2024 Jun 30;12(7):1341. doi: 10.3390/microorganisms12071341. Microorganisms. 2024. PMID: 39065109 Free PMC article.

6

Structure simplification of the Securinine skeleton reveals the importance of BCD ring system for the cytotoxic activity on HCT116 and HL60 cell lines.

Le Roch M, Afonso D, Chirkin E, Guillory X, Porée FH. Le Roch M, et al. Among authors: chirkin e. Bioorg Med Chem. 2022 Mar 15;58:116658. doi: 10.1016/j.bmc.2022.116658. Epub 2022 Feb 12. Bioorg Med Chem. 2022. PMID: 35183880

7

Viability of a [2 + 2 + 1] Hetero-Pauson-Khand Cycloaddition Strategy toward Securinega Alkaloids: Synthesis of the BCD-Ring Core of Securinine and Related Alkaloids.

Chirkin E, Michel S, Porée FH. Chirkin E, et al. J Org Chem. 2015 Jul 2;80(13):6525-8. doi: 10.1021/acs.joc.5b01118. Epub 2015 Jun 24. J Org Chem. 2015. PMID: 26098882

8

The Securinega alkaloids.

Chirkin E, Atkatlian W, Porée FH. Chirkin E, et al. Alkaloids Chem Biol. 2015;74:1-120. doi: 10.1016/bs.alkal.2014.11.001. Alkaloids Chem Biol. 2015. PMID: 25845059 Review.

9

Chiroptical study and absolute configuration of securinine oxidation products.

Chirkin E, Atkatlian W, Do Q, Gaslonde T, Dufat TH, Michel S, Lemoine P, Genta-Jouve G, Porée FH. Chirkin E, et al. Nat Prod Res. 2015;29(13):1235-42. doi: 10.1080/14786419.2015.1023727. Epub 2015 Mar 19. Nat Prod Res. 2015. PMID: 25790256

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