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Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs.
Saïdani N, Botté CY, Deligny M, Bonneau AL, Reader J, Lasselin R, Merer G, Niepceron A, Brossier F, Cintrat JC, Rousseau B, Birkholtz LM, Cesbron-Delauw MF, Dubremetz JF, Mercier C, Vial H, Lopez R, Maréchal E. Saïdani N, et al. Among authors: cintrat jc. Antimicrob Agents Chemother. 2014 May;58(5):2586-97. doi: 10.1128/AAC.01445-13. Epub 2014 Feb 18. Antimicrob Agents Chemother. 2014. PMID: 24550329 Free PMC article.
ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.
Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J. Wu Y, et al. Among authors: cintrat jc. Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7. Sci Rep. 2017. PMID: 29138439 Free PMC article.
Control of peptide nanotube diameter by chemical modifications of an aromatic residue involved in a single close contact.
Tarabout C, Roux S, Gobeaux F, Fay N, Pouget E, Meriadec C, Ligeti M, Thomas D, IJsselstijn M, Besselievre F, Buisson DA, Verbavatz JM, Petitjean M, Valéry C, Perrin L, Rousseau B, Artzner F, Paternostre M, Cintrat JC. Tarabout C, et al. Among authors: cintrat jc. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7679-84. doi: 10.1073/pnas.1017343108. Epub 2011 Apr 25. Proc Natl Acad Sci U S A. 2011. PMID: 21518895 Free PMC article.
Structure-Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin.
Abdelkafi H, Michau A, Pons V, Ngadjeua F, Clerget A, Ait Ouarab L, Buisson DA, Montoir D, Caramelle L, Gillet D, Barbier J, Cintrat JC. Abdelkafi H, et al. Among authors: cintrat jc. J Med Chem. 2020 Aug 13;63(15):8114-8133. doi: 10.1021/acs.jmedchem.0c00298. Epub 2020 Jul 27. J Med Chem. 2020. PMID: 32648758 Free article.
65 results