Yu WP - Search Results

1

The APP intracellular domain promotes LRRK2 expression to enable feed-forward neurodegenerative mechanisms in Parkinson's disease.

Zhang ZW, Tu H, Jiang M, Vanan S, Chia SY, Jang SE, Saw WT, Ong ZW, Ma DR, Zhou ZD, Xu J, Guo KH, Yu WP, Ling SC, Margolin RA, Chain DG, Zeng L, Tan EK. Zhang ZW, et al. Among authors: yu wp. Sci Signal. 2022 Aug 23;15(748):eabk3411. doi: 10.1126/scisignal.abk3411. Epub 2022 Aug 23. Sci Signal. 2022. PMID: 35998231

2

PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration.

Zeng L, Si X, Yu WP, Le HT, Ng KP, Teng RM, Ryan K, Wang DZ, Ponniah S, Pallen CJ. Zeng L, et al. Among authors: yu wp. J Cell Biol. 2003 Jan 6;160(1):137-46. doi: 10.1083/jcb.200206049. Epub 2003 Jan 6. J Cell Biol. 2003. PMID: 12515828 Free PMC article.

3

Amyloid precursor protein regulates neurogenesis by antagonizing miR-574-5p in the developing cerebral cortex.

Zhang W, Thevapriya S, Kim PJ, Yu WP, Je HS, Tan EK, Zeng L. Zhang W, et al. Among authors: yu wp. Nat Commun. 2014 Mar 3;5:3330. doi: 10.1038/ncomms4330. Nat Commun. 2014. PMID: 24584353 Free article.

4

Amyloid precursor protein intracellular domain-dependent regulation of FOXO3a inhibits adult hippocampal neurogenesis.

Jiang M, Vanan S, Tu HT, Zhang W, Zhang ZW, Chia SY, Jang SE, Zeng XX, Yu WP, Xu J, Guo KH, Zeng L. Jiang M, et al. Among authors: yu wp. Neurobiol Aging. 2020 Nov;95:250-263. doi: 10.1016/j.neurobiolaging.2020.07.031. Epub 2020 Aug 4. Neurobiol Aging. 2020. PMID: 32866886

5

Altered striatal dopamine levels in Parkinson's disease VPS35 D620N mutant transgenic aged mice.

Vanan S, Zeng X, Chia SY, Varnäs K, Jiang M, Zhang K, Saw WT, Padmanabhan P, Yu WP, Zhou ZD, Halldin C, Gulyás B, Tan EK, Zeng L. Vanan S, et al. Among authors: yu wp. Mol Brain. 2020 Dec 1;13(1):164. doi: 10.1186/s13041-020-00704-3. Mol Brain. 2020. PMID: 33261640 Free PMC article.

6

Impaired neurogenesis in the hippocampus of an adult VPS35 mutant mouse model of Parkinson's disease through interaction with APP.

Jiang M, Tu HT, Zhang K, Zhang W, Yu WP, Xu J, Tan EK, Guo KH, Zeng L. Jiang M, et al. Among authors: yu wp. Neurobiol Dis. 2021 Jun;153:105313. doi: 10.1016/j.nbd.2021.105313. Epub 2021 Feb 24. Neurobiol Dis. 2021. PMID: 33636388 Free article.

7

Expression of a constitutively active p38α mutant in mice causes early death, anemia, and accumulation of immunosuppressive cells.

Darlyuk-Saadon I, Heng CKM, Bai C, Gilad N, Yu WP, Meng Huang Mok M, Wong WSF, Engelberg D. Darlyuk-Saadon I, et al. Among authors: yu wp. FEBS J. 2021 Jul;288(13):3978-3999. doi: 10.1111/febs.15697. Epub 2021 Jan 22. FEBS J. 2021. PMID: 33410203 Free article.

8

Loss of Ca_V1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memory.

Zhai J, Navakkode S, Yeow SQZ, Krishna-K K, Liang MC, Koh JH, Wong RX, Yu WP, Sajikumar S, Huang H, Soong TW. Zhai J, et al. Among authors: yu wp. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2203883119. doi: 10.1073/pnas.2203883119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914168 Free PMC article.

9

Active p38α causes macrovesicular fatty liver in mice.

Darlyuk-Saadon I, Bai C, Heng CKM, Gilad N, Yu WP, Lim PY, Cazenave-Gassiot A, Zhang Y, Wong WSF, Engelberg D. Darlyuk-Saadon I, et al. Among authors: yu wp. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2018069118. doi: 10.1073/pnas.2018069118. Proc Natl Acad Sci U S A. 2021. PMID: 33811139 Free PMC article.

10

Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus.

Lee SH, Lim CL, Shen W, Tan SMX, Woo ARE, Yap YHY, Sian CAS, Goh WWB, Yu WP, Li L, Lin VCL. Lee SH, et al. Among authors: yu wp. BMC Biol. 2022 Oct 5;20(1):222. doi: 10.1186/s12915-022-01410-3. BMC Biol. 2022. PMID: 36199058 Free PMC article.

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