Heljasvaara R - Search Results

1

Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis.

Martínez-Nieto GA, Teppo HR, Petrelius N, Izzi V, Devarajan R, Petäistö T, Liu H, Kim KS, Karppinen SM, Ruotsalainen H, Koivunen J, Mäki JM, Walker GC, Pihlajaniemi T, Gullberg D, Heljasvaara R. Martínez-Nieto GA, et al. Among authors: heljasvaara r. Front Oncol. 2022 Aug 8;12:981009. doi: 10.3389/fonc.2022.981009. eCollection 2022. Front Oncol. 2022. PMID: 36003785 Free PMC article.

2

Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13.

Nyberg P, Heikkilä P, Sorsa T, Luostarinen J, Heljasvaara R, Stenman UH, Pihlajaniemi T, Salo T. Nyberg P, et al. Among authors: heljasvaara r. J Biol Chem. 2003 Jun 20;278(25):22404-11. doi: 10.1074/jbc.M210325200. Epub 2003 Apr 10. J Biol Chem. 2003. PMID: 12690120 Free article.

3

Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases.

Heljasvaara R, Nyberg P, Luostarinen J, Parikka M, Heikkilä P, Rehn M, Sorsa T, Salo T, Pihlajaniemi T. Heljasvaara R, et al. Exp Cell Res. 2005 Jul 15;307(2):292-304. doi: 10.1016/j.yexcr.2005.03.021. Exp Cell Res. 2005. PMID: 15950618

4

Collagen XVIII/endostatin shows a ubiquitous distribution in human ocular tissues and endostatin-containing fragments accumulate in ocular fluid samples.

Määttä M, Heljasvaara R, Pihlajaniemi T, Uusitalo M. Määttä M, et al. Among authors: heljasvaara r. Graefes Arch Clin Exp Ophthalmol. 2007 Jan;245(1):74-81. doi: 10.1007/s00417-006-0281-y. Epub 2006 Apr 13. Graefes Arch Clin Exp Ophthalmol. 2007. PMID: 16612638

5

Differential expression of collagen types XVIII/endostatin and XV in normal, keratoconus, and scarred human corneas.

Määttä M, Heljasvaara R, Sormunen R, Pihlajaniemi T, Autio-Harmainen H, Tervo T. Määttä M, et al. Among authors: heljasvaara r. Cornea. 2006 Apr;25(3):341-9. doi: 10.1097/01.ico.0000178729.57435.96. Cornea. 2006. PMID: 16633037

6

Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice.

Brideau G, Mäkinen MJ, Elamaa H, Tu H, Nilsson G, Alitalo K, Pihlajaniemi T, Heljasvaara R. Brideau G, et al. Among authors: heljasvaara r. Cancer Res. 2007 Dec 15;67(24):11528-35. doi: 10.1158/0008-5472.CAN-07-1458. Cancer Res. 2007. PMID: 18089781

7

Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing.

Seppinen L, Sormunen R, Soini Y, Elamaa H, Heljasvaara R, Pihlajaniemi T. Seppinen L, et al. Among authors: heljasvaara r. Matrix Biol. 2008 Jul;27(6):535-46. doi: 10.1016/j.matbio.2008.03.003. Epub 2008 Apr 1. Matrix Biol. 2008. PMID: 18455382

8

Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.

Rasi K, Piuhola J, Czabanka M, Sormunen R, Ilves M, Leskinen H, Rysä J, Kerkelä R, Janmey P, Heljasvaara R, Peuhkurinen K, Vuolteenaho O, Ruskoaho H, Vajkoczy P, Pihlajaniemi T, Eklund L. Rasi K, et al. Among authors: heljasvaara r. Circ Res. 2010 Nov 12;107(10):1241-52. doi: 10.1161/CIRCRESAHA.110.222133. Epub 2010 Sep 16. Circ Res. 2010. PMID: 20847313

9

Serpin peptidase inhibitor clade A member 1 (SerpinA1) is a novel biomarker for progression of cutaneous squamous cell carcinoma.

Farshchian M, Kivisaari A, Ala-Aho R, Riihilä P, Kallajoki M, Grénman R, Peltonen J, Pihlajaniemi T, Heljasvaara R, Kähäri VM. Farshchian M, et al. Among authors: heljasvaara r. Am J Pathol. 2011 Sep;179(3):1110-9. doi: 10.1016/j.ajpath.2011.05.012. Epub 2011 Jul 1. Am J Pathol. 2011. PMID: 21723846 Free PMC article.

10

Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.

Holopainen T, López-Alpuche V, Zheng W, Heljasvaara R, Jones D, He Y, Tvorogov D, D'Amico G, Wiener Z, Andersson LC, Pihlajaniemi T, Min W, Alitalo K. Holopainen T, et al. Among authors: heljasvaara r. Cancer Res. 2012 Jul 15;72(14):3512-21. doi: 10.1158/0008-5472.CAN-11-1070. Epub 2012 May 16. Cancer Res. 2012. PMID: 22593188

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