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Page 1
Combined docking and machine learning identify key molecular determinants of ligand pharmacological activity on β2 adrenoceptor.
Jiménez-Rosés M, Morgan BA, Jimenez Sigstad M, Tran TDZ, Srivastava R, Bunsuz A, Borrega-Román L, Hompluem P, Cullum SA, Harwood CR, Koers EJ, Sykes DA, Styles IB, Veprintsev DB. Jiménez-Rosés M, et al. Among authors: koers ej. Pharmacol Res Perspect. 2022 Oct;10(5):e00994. doi: 10.1002/prp2.994. Pharmacol Res Perspect. 2022. PMID: 36029004 Free PMC article.
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
Sarott RC, Westphal MV, Pfaff P, Korn C, Sykes DA, Gazzi T, Brennecke B, Atz K, Weise M, Mostinski Y, Hompluem P, Koers E, Miljuš T, Roth NJ, Asmelash H, Vong MC, Piovesan J, Guba W, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Benito-Cuesta I, Grande T, Ruiz de Martı N Esteban S, Yeliseev A, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Yuan CY, Drobyski WR, Saroz Y, Grimsey N, Honer M, Fingerle J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, McCormick PJ, Ullmer C, Oddi S, Maccarrone M, Veprintsev DB, Nazaré M, Grether U, Carreira EM. Sarott RC, et al. J Am Chem Soc. 2020 Oct 7;142(40):16953-16964. doi: 10.1021/jacs.0c05587. Epub 2020 Sep 29. J Am Chem Soc. 2020. PMID: 32902974
Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.
Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Honer M, Fingerle J, Scheffel J, Broichhagen J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, Ullmer C, McCormick PJ, Oddi S, Spaink HP, Maccarrone M, Veprintsev DB, Carreira EM, Grether U, Nazaré M. Gazzi T, et al. Among authors: koers ej. Chem Sci. 2022 Apr 1;13(19):5539-5545. doi: 10.1039/d1sc06659e. eCollection 2022 May 18. Chem Sci. 2022. PMID: 35694350 Free PMC article.
Protein chain collapse modulation and folding stimulation by GroEL-ES.
Naqvi MM, Avellaneda MJ, Roth A, Koers EJ, Roland A, Sunderlikova V, Kramer G, Rye HS, Tans SJ. Naqvi MM, et al. Among authors: koers ej. Sci Adv. 2022 Mar 4;8(9):eabl6293. doi: 10.1126/sciadv.abl6293. Epub 2022 Mar 4. Sci Adv. 2022. PMID: 35245117 Free PMC article.
Protein Tethering for Single-Molecule Force Spectroscopy.
Avellaneda MJ, Koers EJ, Sunderlikova V, Tans SJ. Avellaneda MJ, et al. Among authors: koers ej. Methods Mol Biol. 2024;2694:57-67. doi: 10.1007/978-1-0716-3377-9_3. Methods Mol Biol. 2024. PMID: 37823999
Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f.
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Verprintsev DB, Vaidehi N, Weyand SN, Tate CG. Gusach A, et al. Among authors: koers ej. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.547762. doi: 10.1101/2023.07.07.547762. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 30;15(1):7555. doi: 10.1038/s41467-024-51793-w. PMID: 37461561 Free PMC article. Updated. Preprint.
22 results