Carlos JAEG - Search Results

1

AD80, a multikinase inhibitor, as a potential drug candidate for colorectal cancer therapy.

de Almeida LC, Carlos JAEG, Rezende-Teixeira P, Machado-Neto JA, Costa-Lotufo LV. de Almeida LC, et al. Among authors: carlos jaeg. Life Sci. 2022 Nov 1;308:120911. doi: 10.1016/j.lfs.2022.120911. Epub 2022 Aug 27. Life Sci. 2022. PMID: 36030982 Free article.

2

Reversine exhibits antineoplastic activity in JAK2^V617F-positive myeloproliferative neoplasms.

Lima K, Carlos JAEG, Alves-Paiva RM, Vicari HP, Souza Santos FP, Hamerschlak N, Costa-Lotufo LV, Traina F, Machado-Neto JA. Lima K, et al. Among authors: carlos jaeg. Sci Rep. 2019 Jul 9;9(1):9895. doi: 10.1038/s41598-019-46163-2. Sci Rep. 2019. PMID: 31289316 Free PMC article.

3

Reversine exerts cytotoxic effects through multiple cell death mechanisms in acute lymphoblastic leukemia.

Carlos JAEG, Lima K, Coelho-Silva JL, de Melo Alves-Paiva R, Moreno NC, Vicari HP, de Souza Santos FP, Hamerschlak N, Costa-Lotufo LV, Traina F, Machado-Neto JA. Carlos JAEG, et al. Cell Oncol (Dordr). 2020 Dec;43(6):1191-1201. doi: 10.1007/s13402-020-00551-3. Epub 2020 Aug 28. Cell Oncol (Dordr). 2020. PMID: 32857324

4

AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis.

Carlos JAEG, Lima K, Costa-Lotufo LV, Leitão A, Machado-Neto JA. Carlos JAEG, et al. Invest New Drugs. 2021 Aug;39(4):1139-1149. doi: 10.1007/s10637-021-01066-w. Epub 2021 Jan 21. Invest New Drugs. 2021. PMID: 33475938

5

Obatoclax reduces cell viability of acute myeloid leukemia cell lines independently of their sensitivity to venetoclax.

Lima K, Vicari HP, Carlos JAEG, da Silva JCL, Figueiredo-Pontes LL, Rego EM, Machado-Neto JA. Lima K, et al. Among authors: carlos jaeg. Hematol Transfus Cell Ther. 2022 Jan-Mar;44(1):124-127. doi: 10.1016/j.htct.2021.01.004. Epub 2021 Mar 13. Hematol Transfus Cell Ther. 2022. PMID: 33753045 Free PMC article. No abstract available.

6

miRNAs as prognostic predictors in acute myeloid leukemia.

Machado-Neto JA, Carlos JAEG, Lima K. Machado-Neto JA, et al. Among authors: carlos jaeg. Transl Cancer Res. 2023 Jul 31;12(7):1656-1659. doi: 10.21037/tcr-23-716. Epub 2023 Jun 25. Transl Cancer Res. 2023. PMID: 37588737 Free PMC article. No abstract available.

7

Antineoplastic effects of pharmacological inhibitors of aurora kinases in CSF3R^T618I-driven cells.

Parducci NS, Garnique ADMB, Lima K, Carlos JAEG, Fonseca NP, de Miranda LBL, de Almeida BO, Rego EM, Traina F, Machado-Neto JA. Parducci NS, et al. Among authors: carlos jaeg. Blood Cells Mol Dis. 2024 Jan;104:102799. doi: 10.1016/j.bcmd.2023.102799. Epub 2023 Oct 9. Blood Cells Mol Dis. 2024. PMID: 37839173

8

The survivin/XIAP suppressant YM155 impairs clonal growth and induces apoptosis in JAK2^V617F cells.

Carlos JAEG, Lima K, Rego EM, Costa-Lotufo LV, Machado-Neto JA. Carlos JAEG, et al. Hematol Transfus Cell Ther. 2024 Dec;46 Suppl 6(Suppl 6):S217-S227. doi: 10.1016/j.htct.2024.05.012. Epub 2024 Sep 7. Hematol Transfus Cell Ther. 2024. PMID: 39261151 Free PMC article.

9

Dona Flor and her two husbands: Discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment.

Waitman KB, Martin HJ, Carlos JAEG, Braga RC, Souza VAM, Melo-Filho CC, Hilscher S, Toledo MFZJ, Tavares MT, Costa-Lotufo LV, Machado-Neto JA, Schutkowski M, Sippl W, Kronenberger T, Alves VM, Parise-Filho R, Muratov EN. Waitman KB, et al. Among authors: carlos jaeg. bioRxiv [Preprint]. 2024 Dec 5:2024.11.30.626092. doi: 10.1101/2024.11.30.626092. bioRxiv. 2024. PMID: 39677737 Free PMC article. Preprint.

10

HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents.

Waitman KB, de Almeida LC, Primi MC, Carlos JAEG, Ruiz C, Kronenberger T, Laufer S, Goettert MI, Poso A, Vassiliades SV, de Souza VAM, Toledo MFZJ, Hassimotto NMA, Cameron MD, Bannister TD, Costa-Lotufo LV, Machado-Neto JA, Tavares MT, Parise-Filho R. Waitman KB, et al. Among authors: carlos jaeg. Eur J Med Chem. 2024 Jan 5;263:115935. doi: 10.1016/j.ejmech.2023.115935. Epub 2023 Nov 10. Eur J Med Chem. 2024. PMID: 37989057

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