Wajant H - Search Results

1

A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer's disease mouse model.

Ortí-Casañ N, Zuhorn IS, Naudé PJW, De Deyn PP, van Schaik PEM, Wajant H, Eisel ULM. Ortí-Casañ N, et al. Among authors: wajant h. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2201137119. doi: 10.1073/pnas.2201137119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037389 Free PMC article.

2

Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis.

Chopra M, Riedel SS, Biehl M, Krieger S, von Krosigk V, Bäuerlein CA, Brede C, Jordan Garrote AL, Kraus S, Schäfer V, Ritz M, Mattenheimer K, Degla A, Mottok A, Einsele H, Wajant H, Beilhack A. Chopra M, et al. Among authors: wajant h. Carcinogenesis. 2013 Jun;34(6):1296-303. doi: 10.1093/carcin/bgt038. Epub 2013 Feb 5. Carcinogenesis. 2013. PMID: 23385062

3

Principles of antibody-mediated TNF receptor activation.

Wajant H. Wajant H. Cell Death Differ. 2015 Nov;22(11):1727-41. doi: 10.1038/cdd.2015.109. Epub 2015 Aug 21. Cell Death Differ. 2015. PMID: 26292758 Free PMC article. Review.

4

Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice.

Lamontain V, Schmid T, Weber-Steffens D, Zeller D, Jenei-Lanzl Z, Wajant H, Straub RH, Männel DN. Lamontain V, et al. Among authors: wajant h. Cell Mol Immunol. 2019 Jan;16(1):65-74. doi: 10.1038/cmi.2017.138. Epub 2018 Jan 29. Cell Mol Immunol. 2019. PMID: 29375132 Free PMC article.

5

Lack of Evidence for a Direct Interaction of Progranulin and Tumor Necrosis Factor Receptor-1 and Tumor Necrosis Factor Receptor-2 From Cellular Binding Studies.

Lang I, Füllsack S, Wajant H. Lang I, et al. Among authors: wajant h. Front Immunol. 2018 Apr 23;9:793. doi: 10.3389/fimmu.2018.00793. eCollection 2018. Front Immunol. 2018. PMID: 29740434 Free PMC article.

6

Tumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target.

Medler J, Wajant H. Medler J, et al. Among authors: wajant h. Expert Opin Ther Targets. 2019 Apr;23(4):295-307. doi: 10.1080/14728222.2019.1586886. Epub 2019 Mar 19. Expert Opin Ther Targets. 2019. PMID: 30856027 Review.

7

A systems-biology model of the tumor necrosis factor (TNF) interactions with TNF receptor 1 and 2.

Prada JP, Wangorsch G, Kucka K, Lang I, Dandekar T, Wajant H. Prada JP, et al. Among authors: wajant h. Bioinformatics. 2021 May 5;37(5):669-676. doi: 10.1093/bioinformatics/btaa844. Bioinformatics. 2021. PMID: 32991680

8

Effects of selective TNFR1 inhibition or TNFR2 stimulation, compared to non-selective TNF inhibition, on (neuro)inflammation and behavior after myocardial infarction in male mice.

Gouweleeuw L, Wajant H, Maier O, Eisel ULM, Blankesteijn WM, Schoemaker RG. Gouweleeuw L, et al. Among authors: wajant h. Brain Behav Immun. 2021 Mar;93:156-171. doi: 10.1016/j.bbi.2021.01.001. Epub 2021 Jan 12. Brain Behav Immun. 2021. PMID: 33444731 Free article.

9

Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2-expressing Treg cells.

Ronin E, Pouchy C, Khosravi M, Hilaire M, Grégoire S, Casrouge A, Kassem S, Sleurs D, Martin GH, Chanson N, Lombardi Y, Lalle G, Wajant H, Auffray C, Lucas B, Marodon G, Grinberg-Bleyer Y, Salomon BL. Ronin E, et al. Among authors: wajant h. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2014043118. doi: 10.1073/pnas.2014043118. Proc Natl Acad Sci U S A. 2021. PMID: 33766913 Free PMC article.

10

Membrane lymphotoxin-α₂β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist.

Kucka K, Lang I, Zhang T, Siegmund D, Medler J, Wajant H. Kucka K, et al. Among authors: wajant h. Cell Death Dis. 2021 Apr 6;12(4):360. doi: 10.1038/s41419-021-03633-8. Cell Death Dis. 2021. PMID: 33824270 Free PMC article.

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