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Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations.
Choudhary GS, Pellagatti A, Agianian B, Smith MA, Bhagat TD, Gordon-Mitchell S, Sahu S, Pandey S, Shah N, Aluri S, Aggarwal R, Aminov S, Schwartz L, Steeples V, Booher RN, Ramachandra M, Samson M, Carbajal M, Pradhan K, Bowman TV, Pillai MM, Will B, Wickrema A, Shastri A, Bradley RK, Martell RE, Steidl UG, Gavathiotis E, Boultwood J, Starczynowski DT, Verma A. Choudhary GS, et al. Among authors: starczynowski dt. Elife. 2022 Aug 30;11:e78136. doi: 10.7554/eLife.78136. Elife. 2022. PMID: 36040792 Free PMC article.
Deregulation of microRNAs in myelodysplastic syndrome.
Rhyasen GW, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Leukemia. 2012 Jan;26(1):13-22. doi: 10.1038/leu.2011.221. Epub 2011 Aug 19. Leukemia. 2012. PMID: 21852786 Review.
Implication of microRNAs in the pathogenesis of MDS.
Fang J, Varney M, Starczynowski DT. Fang J, et al. Among authors: starczynowski dt. Curr Pharm Des. 2012;18(22):3170-9. doi: 10.2174/1381612811209023170. Curr Pharm Des. 2012. PMID: 22571695 Free PMC article. Review.
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.
Rhyasen GW, Bolanos L, Fang J, Jerez A, Wunderlich M, Rigolino C, Mathews L, Ferrer M, Southall N, Guha R, Keller J, Thomas C, Beverly LJ, Cortelezzi A, Oliva EN, Cuzzola M, Maciejewski JP, Mulloy JC, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Cancer Cell. 2013 Jul 8;24(1):90-104. doi: 10.1016/j.ccr.2013.05.006. Cancer Cell. 2013. PMID: 23845443 Free PMC article.
Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes.
Gañán-Gómez I, Wei Y, Starczynowski DT, Colla S, Yang H, Cabrero-Calvo M, Bohannan ZS, Verma A, Steidl U, Garcia-Manero G. Gañán-Gómez I, et al. Among authors: starczynowski dt. Leukemia. 2015 Jul;29(7):1458-69. doi: 10.1038/leu.2015.69. Epub 2015 Mar 12. Leukemia. 2015. PMID: 25761935 Free PMC article. Review.
Deconstructing innate immune signaling in myelodysplastic syndromes.
Varney ME, Melgar K, Niederkorn M, Smith M, Barreyro L, Starczynowski DT. Varney ME, et al. Among authors: starczynowski dt. Exp Hematol. 2015 Aug;43(8):587-598. doi: 10.1016/j.exphem.2015.05.016. Epub 2015 Jul 2. Exp Hematol. 2015. PMID: 26143580 Free PMC article. Review.
Chronic immune response dysregulation in MDS pathogenesis.
Barreyro L, Chlon TM, Starczynowski DT. Barreyro L, et al. Among authors: starczynowski dt. Blood. 2018 Oct 11;132(15):1553-1560. doi: 10.1182/blood-2018-03-784116. Epub 2018 Aug 13. Blood. 2018. PMID: 30104218 Free PMC article. Review.
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.
Smith MA, Choudhary GS, Pellagatti A, Choi K, Bolanos LC, Bhagat TD, Gordon-Mitchell S, Von Ahrens D, Pradhan K, Steeples V, Kim S, Steidl U, Walter M, Fraser IDC, Kulkarni A, Salomonis N, Komurov K, Boultwood J, Verma A, Starczynowski DT. Smith MA, et al. Among authors: starczynowski dt. Nat Cell Biol. 2019 May;21(5):640-650. doi: 10.1038/s41556-019-0314-5. Epub 2019 Apr 22. Nat Cell Biol. 2019. PMID: 31011167 Free PMC article.
100 results