Iyer DR - Search Results

1

CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair.

Li F, Sarangi P, Iyer DR, Feng H, Moreau L, Nguyen H, Clairmont C, D'Andrea AD. Li F, et al. Among authors: iyer dr. Cell Rep. 2022 Aug 30;40(9):111297. doi: 10.1016/j.celrep.2022.111297. Cell Rep. 2022. PMID: 36044844 Free PMC article.

2

TGFβ pathway is required for viable gestation of Fanconi anemia embryos.

Rodríguez A, Epperly M, Filiatrault J, Velázquez M, Yang C, McQueen K, Sambel LA, Nguyen H, Iyer DR, Juárez U, Ayala-Zambrano C, Martignetti DB, Frías S, Fisher R, Parmar K, Greenberger JS, D'Andrea AD. Rodríguez A, et al. Among authors: iyer dr. PLoS Genet. 2022 Nov 28;18(11):e1010459. doi: 10.1371/journal.pgen.1010459. eCollection 2022 Nov. PLoS Genet. 2022. PMID: 36441774 Free PMC article.

3

CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining.

Iyer DR, Harada N, Clairmont C, Jiang L, Martignetti D, Nguyen H, He YJ, Chowdhury D, D'Andrea AD. Iyer DR, et al. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2214935119. doi: 10.1073/pnas.2214935119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442094 Free PMC article.

4

Fork restart: unloading FANCD2 to travel ahead.

Iyer DR, D'Andrea AD. Iyer DR, et al. Mol Cell. 2023 Oct 19;83(20):3590-3592. doi: 10.1016/j.molcel.2023.09.027. Mol Cell. 2023. PMID: 37863027 Free article.

5

Single-Stranded DNA Gap Accumulation Is a Functional Biomarker for USP1 Inhibitor Sensitivity.

da Costa AA, Somuncu O, Ravindranathan R, Mukkavalli S, Martignetti DB, Nguyen H, Jiao Y, Lamarre BP, Sadatrezaei G, Moreau L, Liu J, Iyer DR, Lazaro JB, Shapiro GI, Parmar K, D'Andrea AD. da Costa AA, et al. Among authors: iyer dr. Cancer Res. 2024 Oct 15;84(20):3435-3446. doi: 10.1158/0008-5472.CAN-23-4007. Cancer Res. 2024. PMID: 38885312 Free PMC article.

6

The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway.

Harada N, Asada S, Jiang L, Nguyen H, Moreau L, Marina RJ, Adelman K, Iyer DR, D'Andrea AD. Harada N, et al. Among authors: iyer dr. Mol Cell. 2024 Jul 25;84(14):2618-2633.e10. doi: 10.1016/j.molcel.2024.06.031. Epub 2024 Jul 17. Mol Cell. 2024. PMID: 39025073 Free PMC article.

7

Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System.

Santaguida S, Richardson A, Iyer DR, M'Saad O, Zasadil L, Knouse KA, Wong YL, Rhind N, Desai A, Amon A. Santaguida S, et al. Among authors: iyer dr. Dev Cell. 2017 Jun 19;41(6):638-651.e5. doi: 10.1016/j.devcel.2017.05.022. Dev Cell. 2017. PMID: 28633018 Free PMC article.

8

Checkpoint regulation of replication forks: global or local?

Iyer DR, Rhind N. Iyer DR, et al. Biochem Soc Trans. 2013 Dec;41(6):1701-5. doi: 10.1042/BST20130197. Biochem Soc Trans. 2013. PMID: 24256278 Free PMC article. Review.

9

The Intra-S Checkpoint Responses to DNA Damage.

Iyer DR, Rhind N. Iyer DR, et al. Genes (Basel). 2017 Feb 17;8(2):74. doi: 10.3390/genes8020074. Genes (Basel). 2017. PMID: 28218681 Free PMC article. Review.

10

Global increase in replication fork speed during a p57^KIP2-regulated erythroid cell fate switch.

Hwang Y, Futran M, Hidalgo D, Pop R, Iyer DR, Scully R, Rhind N, Socolovsky M. Hwang Y, et al. Among authors: iyer dr. Sci Adv. 2017 May 26;3(5):e1700298. doi: 10.1126/sciadv.1700298. eCollection 2017 May. Sci Adv. 2017. PMID: 28560351 Free PMC article.

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