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Page 1
Dysregulated naive B cells and de novo autoreactivity in severe COVID-19.
Woodruff MC, Ramonell RP, Haddad NS, Anam FA, Rudolph ME, Walker TA, Truong AD, Dixit AN, Han JE, Cabrera-Mora M, Runnstrom MC, Bugrovsky R, Hom J, Connolly EC, Albizua I, Javia V, Cashman KS, Nguyen DC, Kyu S, Singh Saini A, Piazza M, Tipton CM, Khosroshahi A, Gibson G, Martin GS, Maier CL, Esper A, Jenks SA, Lee FE, Sanz I. Woodruff MC, et al. Among authors: anam fa. Nature. 2022 Nov;611(7934):139-147. doi: 10.1038/s41586-022-05273-0. Epub 2022 Aug 31. Nature. 2022. PMID: 36044993 Free PMC article.
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE Jr, Hu WT, Lee FE, Sanz I. Woodruff MC, et al. Among authors: anam fa. Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7. Nat Immunol. 2020. PMID: 33028979 Free PMC article.
One-Stop Serum Assay Identifies COVID-19 Disease Severity and Vaccination Responses.
Haddad NS, Nguyen DC, Kuruvilla ME, Morrison-Porter A, Anam F, Cashman KS, Ramonell RP, Kyu S, Saini AS, Cabrera-Mora M, Derrico A, Alter D, Roback JD, Horwath M, O'Keefe JB, Wu HM, Wong AI, Dretler AW, Gripaldo R, Lane AN, Wu H, Chu HY, Lee S, Hernandez M, Engineer V, Varghese J, Patel R, Jalal A, French V, Guysenov I, Lane CE, Mengistsu T, Normile KE, Mnzava O, Le S, Sanz I, Daiss JL, Lee FE. Haddad NS, et al. Immunohorizons. 2021 May 17;5(5):322-335. doi: 10.4049/immunohorizons.2100011. Immunohorizons. 2021. PMID: 34001652 Free PMC article.
Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection.
Haddad NS, Nguyen DC, Kuruvilla ME, Morrison-Porter A, Anam F, Cashman KS, Ramonell RP, Kyu S, Saini AS, Cabrera-Mora M, Derrico A, Alter D, Roback JD, Horwath M, O'Keefe JB, Wu HM, Ian Wong AK, Dretler AW, Gripaldo R, Lane AN, Wu H, Lee S, Hernandez M, Engineer V, Varghese J, Le S, Sanz I, Daiss JL, Eun-Hyung Lee F. Haddad NS, et al. bioRxiv [Preprint]. 2020 Dec 6:2020.12.04.410589. doi: 10.1101/2020.12.04.410589. bioRxiv. 2020. PMID: 33299998 Free PMC article. Preprint.
Dominant extrafollicular B cell responses in severe COVID-19 disease correlate with robust viral-specific antibody production but poor clinical outcomes.
Woodruff M, Ramonell R, Cashman K, Nguyen D, Saini A, Haddad N, Ley A, Kyu S, Howell JC, Ozturk T, Lee S, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam F, Sharma M, Wu H, Le S, Jenks S, Tipton CM, Hu W, Lee FE, Sanz I. Woodruff M, et al. medRxiv [Preprint]. 2020 Jun 22:2020.04.29.20083717. doi: 10.1101/2020.04.29.20083717. medRxiv. 2020. Update in: Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z PMID: 32511635 Free PMC article. Updated. Preprint.
Publisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Faliti CE, Van TTP, Anam FA, Cheedarla N, Williams ME, Mishra AK, Usman SY, Woodruff MC, Kraker G, Runnstrom MC, Kyu S, Sanz D, Ahmed H, Ghimire M, Morrison-Porter A, Quehl H, Haddad NS, Chen W, Cheedarla S, Neish AS, Roback JD, Antia R, Hom J, Tipton CM, Lindner JM, Ghosn E, Khurana S, Scharer CD, Khosroshahi A, Lee FE, Sanz I. Faliti CE, et al. Among authors: anam fa. Nat Immunol. 2024 Dec 2. doi: 10.1038/s41590-024-02045-y. Online ahead of print. Nat Immunol. 2024. PMID: 39622950 No abstract available.
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Faliti CE, Van TTP, Anam FA, Cheedarla N, Williams ME, Mishra AK, Usman SY, Woodruff MC, Kraker G, Runnstrom MC, Kyu S, Sanz D, Ahmed H, Ghimire M, Morrison-Porter A, Quehl H, Haddad NS, Chen W, Cheedarla S, Neish AS, Roback JD, Antia R, Hom J, Tipton CM, Lindner JM, Ghosn E, Khurana S, Scharer CD, Khosroshahi A, Lee FE, Sanz I. Faliti CE, et al. Among authors: anam fa. Nat Immunol. 2024 Nov 12. doi: 10.1038/s41590-024-02010-9. Online ahead of print. Nat Immunol. 2024. PMID: 39533072
Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus.
Chen W, Hong SH, Jenks SA, Anam FA, Tipton CM, Woodruff MC, Hom JR, Cashman KS, Faliti CE, Wang X, Kyu S, Wei C, Scharer CD, Mi T, Hicks S, Hartson L, Nguyen DC, Khosroshahi A, Lee S, Wang Y, Bugrovsky R, Ishii Y, Lee FE, Sanz I. Chen W, et al. Among authors: anam fa. Nat Commun. 2024 Mar 1;15(1):1899. doi: 10.1038/s41467-024-46053-w. Nat Commun. 2024. PMID: 38429276 Free PMC article.
SLE Antibody-Secreting Cells Are Characterized by Enhanced Peripheral Maturation and Survival Programs.
Chen W, Hong SH, Jenks SA, Anam FA, Tipton CM, Woodruff MC, Hom JR, Cashman KS, Faliti CE, Wang X, Kyu S, Wei C, Scharer CD, Mi T, Hicks S, Hartson L, Nguyen DC, Khosroshahi A, Lee S, Wang Y, Bugrovsky R, Ishii Y, Lee FE, Sanz I. Chen W, et al. Among authors: anam fa. Res Sq [Preprint]. 2023 Jun 27:rs.3.rs-3016327. doi: 10.21203/rs.3.rs-3016327/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Mar 1;15(1):1899. doi: 10.1038/s41467-024-46053-w PMID: 37461641 Free PMC article. Updated. Preprint.
Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID.
Woodruff MC, Bonham KS, Anam FA, Walker TA, Faliti CE, Ishii Y, Kaminski CY, Ruunstrom MC, Cooper KR, Truong AD, Dixit AN, Han JE, Ramonell RP, Haddad NS, Rudolph ME, Yalavarthi S, Betin V, Natoli T, Navaz S, Jenks SA, Zuo Y, Knight JS, Khosroshahi A, Lee FE, Sanz I. Woodruff MC, et al. Among authors: anam fa. Nat Commun. 2023 Jul 14;14(1):4201. doi: 10.1038/s41467-023-40012-7. Nat Commun. 2023. PMID: 37452024 Free PMC article.
12 results