Glennon EB - Search Results

1

Disruption of the VAPB-PTPIP51 ER-mitochondria tethering proteins in post-mortem human amyotrophic lateral sclerosis.

Hartopp N, Lau DHW, Martin-Guerrero SM, Markovinovic A, Mórotz GM, Greig J, Glennon EB, Troakes C, Gomez-Suaga P, Noble W, Miller CCJ. Hartopp N, et al. Among authors: glennon eb. Front Cell Dev Biol. 2022 Aug 16;10:950767. doi: 10.3389/fcell.2022.950767. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36051435 Free PMC article.

2

Disruption of ER-mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis.

Lau DHW, Hartopp N, Welsh NJ, Mueller S, Glennon EB, Mórotz GM, Annibali A, Gomez-Suaga P, Stoica R, Paillusson S, Miller CCJ. Lau DHW, et al. Among authors: glennon eb. Cell Death Dis. 2018 Feb 28;9(3):327. doi: 10.1038/s41419-017-0022-7. Cell Death Dis. 2018. PMID: 29491392 Free PMC article. Review.

3

The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity.

Gómez-Suaga P, Pérez-Nievas BG, Glennon EB, Lau DHW, Paillusson S, Mórotz GM, Calì T, Pizzo P, Noble W, Miller CCJ. Gómez-Suaga P, et al. Among authors: glennon eb. Acta Neuropathol Commun. 2019 Mar 6;7(1):35. doi: 10.1186/s40478-019-0688-4. Acta Neuropathol Commun. 2019. PMID: 30841933 Free PMC article.

4

LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains.

Mórotz GM, Glennon EB, Gomez-Suaga P, Lau DHW, Robinson ED, Sedlák É, Vagnoni A, Noble W, Miller CCJ. Mórotz GM, et al. Among authors: glennon eb. Acta Neuropathol Commun. 2019 May 8;7(1):73. doi: 10.1186/s40478-019-0715-5. Acta Neuropathol Commun. 2019. PMID: 31068217 Free PMC article.

5

Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein.

Mórotz GM, Glennon EB, Greig J, Lau DHW, Bhembre N, Mattedi F, Muschalik N, Noble W, Vagnoni A, Miller CCJ. Mórotz GM, et al. Among authors: glennon eb. Acta Neuropathol Commun. 2019 Dec 5;7(1):200. doi: 10.1186/s40478-019-0857-5. Acta Neuropathol Commun. 2019. PMID: 31806024 Free PMC article.

6

Bridging Integrator-1 protein loss in Alzheimer's disease promotes synaptic tau accumulation and disrupts tau release.

Glennon EB, Lau DH, Gabriele RMC, Taylor MF, Troakes C, Opie-Martin S, Elliott C, Killick R, Hanger DP, Perez-Nievas BG, Noble W. Glennon EB, et al. Brain Commun. 2020;2(1):fcaa011. doi: 10.1093/braincomms/fcaa011. Epub 2020 Feb 14. Brain Commun. 2020. PMID: 32500121 Free PMC article.

7

Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production.

Vagnoni A, Glennon EB, Perkinton MS, Gray EH, Noble W, Miller CC. Vagnoni A, et al. Among authors: glennon eb. Hum Mol Genet. 2013 Nov 15;22(22):4646-52. doi: 10.1093/hmg/ddt313. Epub 2013 Jul 3. Hum Mol Genet. 2013. PMID: 23825109 Free PMC article.

8

Identification of a novel interaction of FUS and syntaphilin may explain synaptic and mitochondrial abnormalities caused by ALS mutations.

Salam S, Tacconelli S, Smith BN, Mitchell JC, Glennon E, Nikolaou N, Houart C, Vance C. Salam S, et al. Sci Rep. 2021 Jun 30;11(1):13613. doi: 10.1038/s41598-021-93189-6. Sci Rep. 2021. PMID: 34193962 Free PMC article.

9

Prion protein is decreased in Alzheimer's brain and inversely correlates with BACE1 activity, amyloid-β levels and Braak stage.

Whitehouse IJ, Miners JS, Glennon EB, Kehoe PG, Love S, Kellett KA, Hooper NM. Whitehouse IJ, et al. Among authors: glennon eb. PLoS One. 2013;8(4):e59554. doi: 10.1371/journal.pone.0059554. Epub 2013 Apr 5. PLoS One. 2013. PMID: 23577068 Free PMC article.

10

Alzheimer's disease-related dysregulation of mRNA translation causes key pathological features with ageing.

Ghosh A, Mizuno K, Tiwari SS, Proitsi P, Gomez Perez-Nievas B, Glennon E, Martinez-Nunez RT, Giese KP. Ghosh A, et al. Transl Psychiatry. 2020 Jun 16;10(1):192. doi: 10.1038/s41398-020-00882-7. Transl Psychiatry. 2020. PMID: 32546772 Free PMC article.

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