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A distinct pattern of growth and RAC1 signaling in melanoma brain metastasis cells.
Stejerean-Todoran I, Gimotty PA, Watters A, Brafford P, Krepler C, Godok T, Li H, Bonilla Del Rio Z, Zieseniss A, Katschinski DM, Sertel SM, Rizzoli SO, Garman B, Nathanson KL, Xu X, Chen Q, Oswald JH, Lotem M, Mills GB, Davies MA, Schön MP, Bogeski I, Herlyn M, Vultur A. Stejerean-Todoran I, et al. Among authors: nathanson kl. Neuro Oncol. 2023 Apr 6;25(4):674-686. doi: 10.1093/neuonc/noac212. Neuro Oncol. 2023. PMID: 36054930 Free PMC article.
Active Notch1 confers a transformed phenotype to primary human melanocytes.
Pinnix CC, Lee JT, Liu ZJ, McDaid R, Balint K, Beverly LJ, Brafford PA, Xiao M, Himes B, Zabierowski SE, Yashiro-Ohtani Y, Nathanson KL, Bengston A, Pollock PM, Weeraratna AT, Nickoloff BJ, Pear WS, Capobianco AJ, Herlyn M. Pinnix CC, et al. Among authors: nathanson kl. Cancer Res. 2009 Jul 1;69(13):5312-20. doi: 10.1158/0008-5472.CAN-08-3767. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549918 Free PMC article.
Distinct MHC gene expression patterns during progression of melanoma.
Degenhardt Y, Huang J, Greshock J, Horiates G, Nathanson K, Yang X, Herlyn M, Weber B. Degenhardt Y, et al. Genes Chromosomes Cancer. 2010 Feb;49(2):144-54. doi: 10.1002/gcc.20728. Genes Chromosomes Cancer. 2010. PMID: 19862823 Free PMC article.
Taking the guesswork out of uveal melanoma.
Herlyn M, Nathanson KL. Herlyn M, et al. Among authors: nathanson kl. N Engl J Med. 2010 Dec 2;363(23):2256-7. doi: 10.1056/NEJMe1010681. Epub 2010 Nov 17. N Engl J Med. 2010. PMID: 21083377 No abstract available.
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K.
Villanueva J, Vultur A, Lee JT, Somasundaram R, Fukunaga-Kalabis M, Cipolla AK, Wubbenhorst B, Xu X, Gimotty PA, Kee D, Santiago-Walker AE, Letrero R, D'Andrea K, Pushparajan A, Hayden JE, Brown KD, Laquerre S, McArthur GA, Sosman JA, Nathanson KL, Herlyn M. Villanueva J, et al. Among authors: nathanson kl. Cancer Cell. 2010 Dec 14;18(6):683-95. doi: 10.1016/j.ccr.2010.11.023. Cancer Cell. 2010. PMID: 21156289 Free PMC article.
Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome.
Huang J, Zhang L, Greshock J, Colligon TA, Wang Y, Ward R, Katsaros D, Lassus H, Butzow R, Godwin AK, Testa JR, Nathanson KL, Gimotty PA, Coukos G, Weber BL, Degenhardt Y. Huang J, et al. Among authors: nathanson kl. Genes Chromosomes Cancer. 2011 Aug;50(8):606-18. doi: 10.1002/gcc.20883. Epub 2011 May 11. Genes Chromosomes Cancer. 2011. PMID: 21563232 Free PMC article.
The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells.
Krepler C, Chunduru SK, Halloran MB, He X, Xiao M, Vultur A, Villanueva J, Mitsuuchi Y, Neiman EM, Benetatos C, Nathanson KL, Amaravadi RK, Pehamberger H, McKinlay M, Herlyn M. Krepler C, et al. Among authors: nathanson kl. Clin Cancer Res. 2013 Apr 1;19(7):1784-94. doi: 10.1158/1078-0432.CCR-12-2518. Epub 2013 Feb 12. Clin Cancer Res. 2013. PMID: 23403634 Free PMC article.
381 results