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181 results

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Page 1
Activation of long non-coding RNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins.
Taiana E, Bandini C, Favasuli VK, Ronchetti D, Silvestris I, Puccio N, Todoerti K, Erratico S, Giannandrea D, Bolli N, Amodio N, Ciarrocchi A, Chiaramonte R, Torrente Y, Piva R, Neri A. Taiana E, et al. Among authors: ciarrocchi a. Haematologica. 2023 Jan 1;108(1):219-233. doi: 10.3324/haematol.2022.281167. Haematologica. 2023. PMID: 36073514 Free PMC article.
MiR-146b-5p regulates IL-23 receptor complex expression in chronic lymphocytic leukemia cells.
Matis S, Grazia Recchia A, Colombo M, Cardillo M, Fabbi M, Todoerti K, Bossio S, Fabris S, Cancila V, Massara R, Reverberi D, Emionite L, Cilli M, Cerruti G, Salvi S, Bet P, Pigozzi S, Fiocca R, Ibatici A, Angelucci E, Gentile M, Monti P, Menichini P, Fronza G, Torricelli F, Ciarrocchi A, Neri A, Fais F, Tripodo C, Morabito F, Ferrarini M, Cutrona G. Matis S, et al. Among authors: ciarrocchi a. Blood Adv. 2022 Oct 25;6(20):5593-5612. doi: 10.1182/bloodadvances.2021005726. Blood Adv. 2022. PMID: 35819446 Free PMC article. Clinical Trial.
Expression levels of NONO, a nuclear protein primarily involved in paraspeckles function, are associated with several deregulated molecular pathways and poor clinical outcome in multiple myeloma.
Ronchetti D, Favasuli VK, Silvestris I, Todoerti K, Torricelli F, Bolli N, Ciarrocchi A, Taiana E, Neri A. Ronchetti D, et al. Among authors: ciarrocchi a. Discov Oncol. 2022 Nov 11;13(1):124. doi: 10.1007/s12672-022-00582-2. Discov Oncol. 2022. PMID: 36367609 Free PMC article.
Long non-coding RNA mitophagy and ALK-negative anaplastic lymphoma-associated transcript: a novel regulator of mitophagy in T-cell lymphoma.
Mularoni V, Donati B, Tameni A, Manicardi V, Reggiani F, Sauta E, Zanelli M, Tigano M, Vitale E, Torricelli F, Ascani S, Martino G, Inghirami G, Sanguedolce F, Ruffini A, Bavieri A, Luminari S, Pizzi M, Dei Tos AP, Fesce C, Neri A, Ciarrocchi A, Fragliasso V. Mularoni V, et al. Among authors: ciarrocchi a. Haematologica. 2023 Dec 1;108(12):3333-3346. doi: 10.3324/haematol.2022.282552. Haematologica. 2023. PMID: 37381763 Free PMC article.
DIS3 depletion in multiple myeloma causes extensive perturbation in cell cycle progression and centrosome amplification.
Favasuli VK, Ronchetti D, Silvestris I, Puccio N, Fabbiano G, Traini V, Todoerti K, Erratico S, Ciarrocchi A, Fragliasso V, Giannandrea D, Tumiatti F, Chiaramonte R, Torrente Y, Finelli P, Morelli E, Munshi NC, Bolli N, Neri A, Taìana E. Favasuli VK, et al. Among authors: ciarrocchi a. Haematologica. 2024 Jan 1;109(1):231-244. doi: 10.3324/haematol.2023.283274. Haematologica. 2024. PMID: 37439377 Free PMC article.
Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma.
Bandini C, Mereu E, Paradzik T, Labrador M, Maccagno M, Cumerlato M, Oreglia F, Prever L, Manicardi V, Taiana E, Ronchetti D, D'Agostino M, Gay F, Larocca A, Besse L, Merlo GR, Hirsch E, Ciarrocchi A, Inghirami G, Neri A, Piva R. Bandini C, et al. Among authors: ciarrocchi a. Exp Hematol Oncol. 2023 Aug 10;12(1):71. doi: 10.1186/s40164-023-00434-x. Exp Hematol Oncol. 2023. PMID: 37563685 Free PMC article.
HELLS regulates transcription in T-cell lymphomas by reducing unscheduled R-loops and by facilitating RNAPII progression.
Tameni A, Mallia S, Manicardi V, Donati B, Torricelli F, Vitale E, Salviato E, Gambarelli G, Muccioli S, Zanelli M, Ascani S, Martino G, Sanguedolce F, Sauta E, Tamagnini I, Puccio N, Neri A, Ciarrocchi A, Fragliasso V. Tameni A, et al. Among authors: ciarrocchi a. Nucleic Acids Res. 2024 Jun 24;52(11):6171-6182. doi: 10.1093/nar/gkae239. Nucleic Acids Res. 2024. PMID: 38597676 Free PMC article.
Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma.
Puccio N, Manzotti G, Mereu E, Torricelli F, Ronchetti D, Cumerlato M, Craparotta I, Di Rito L, Bolis M, Traini V, Manicardi V, Fragliasso V, Torrente Y, Amodio N, Bolli N, Taiana E, Ciarrocchi A, Piva R, Neri A. Puccio N, et al. Among authors: ciarrocchi a. Haematologica. 2024 Dec 1;109(12):4040-4055. doi: 10.3324/haematol.2024.285470. Haematologica. 2024. PMID: 38988264 Free PMC article.
BET inhibitors (BETi) influence oxidative phosphorylation metabolism by affecting mitochondrial dynamics leading to alterations in apoptotic pathways in triple-negative breast cancer (TNBC) cells.
Rossi T, Iorio E, Chirico M, Pisanu ME, Amodio N, Cantafio MEG, Perrotta I, Colciaghi F, Fiorillo M, Gianferrari A, Puccio N, Neri A, Ciarrocchi A, Pistoni M. Rossi T, et al. Among authors: ciarrocchi a. Cell Prolif. 2024 Dec;57(12):e13730. doi: 10.1111/cpr.13730. Epub 2024 Sep 2. Cell Prolif. 2024. PMID: 39223828 Free PMC article.
181 results