The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells.
Wang Z, Hu H, Heitink L, Rogers K, You Y, Tan T, Suen CLW, Garnham A, Chen H, Lieschke E, Diepstraten ST, Chang C, Chen T, Moujalled D, Sutherland K, Lessene G, Sieber OM, Visvader J, Kelly GL, Strasser A.
Wang Z, et al. Among authors: moujalled d.
Cell Death Differ. 2023 Apr;30(4):1033-1046. doi: 10.1038/s41418-023-01122-3. Epub 2023 Feb 4.
Cell Death Differ. 2023.
PMID: 36739334
Free PMC article.