Liu X - Search Results

1

Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests.

Frank F, Keen MM, Rao A, Bassit L, Liu X, Bowers HB, Patel AB, Cato ML, Sullivan JA, Greenleaf M, Piantadosi A, Lam WA, Hudson WH, Ortlund EA. Frank F, et al. Among authors: liu x. Cell. 2022 Sep 15;185(19):3603-3616.e13. doi: 10.1016/j.cell.2022.08.010. Epub 2022 Aug 29. Cell. 2022. PMID: 36084631 Free PMC article.

2

The nuclear receptor superfamily: A structural perspective.

Weikum ER, Liu X, Ortlund EA. Weikum ER, et al. Among authors: liu x. Protein Sci. 2018 Nov;27(11):1876-1892. doi: 10.1002/pro.3496. Protein Sci. 2018. PMID: 30109749 Free PMC article. Review.

3

First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids.

Liu X, Wang Y, Ortlund EA. Liu X, et al. Mol Pharmacol. 2019 Oct;96(4):408-417. doi: 10.1124/mol.119.116806. Epub 2019 Aug 7. Mol Pharmacol. 2019. PMID: 31391291 Free PMC article.

4

Proline-Rich Acidic Protein 1 (PRAP1) Protects the Gastrointestinal Epithelium From Irradiation-Induced Apoptosis.

Wolfarth AA, Liu X, Darby TM, Boyer DJ, Spizman JB, Owens JA, Chandrasekharan B, Naudin CR, Hanley KZ, Robinson BS, Ortlund EA, Jones RM, Neish AS. Wolfarth AA, et al. Among authors: liu x. Cell Mol Gastroenterol Hepatol. 2020;10(4):713-727. doi: 10.1016/j.jcmgh.2020.06.011. Epub 2020 Jul 3. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32629119 Free PMC article.

5

Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment.

Liu X, Wang Y, Gutierrez JS, Damsker JM, Nagaraju K, Hoffman EP, Ortlund EA. Liu X, et al. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24285-24293. doi: 10.1073/pnas.2006890117. Epub 2020 Sep 11. Proc Natl Acad Sci U S A. 2020. PMID: 32917814 Free PMC article.

6

Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist.

Mays SG, Stec J, Liu X, D'Agostino EH, Whitby RJ, Ortlund EA. Mays SG, et al. Among authors: liu x. Sci Rep. 2020 Dec 17;10(1):22279. doi: 10.1038/s41598-020-79251-9. Sci Rep. 2020. PMID: 33335203 Free PMC article.

7

Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.

Bruno NE, Nwachukwu JC, Srinivasan S, Nettles CC, Izard T, Jin Z, Nowak J, Cameron MD, Boregowda SV, Phinney DG, Elemento O, Liu X, Ortlund EA, Houtman R, Stavreva DA, Hager GL, Kamenecka TM, Kojetin DJ, Nettles KW. Bruno NE, et al. Among authors: liu x. Nat Chem Biol. 2021 Mar;17(3):307-316. doi: 10.1038/s41589-020-00719-w. Epub 2021 Jan 28. Nat Chem Biol. 2021. PMID: 33510451 Free PMC article.

8

Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation.

Frank F, Liu X, Ortlund EA. Frank F, et al. Among authors: liu x. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2024685118. doi: 10.1073/pnas.2024685118. Proc Natl Acad Sci U S A. 2021. PMID: 34285072 Free PMC article.

9

Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.

Liu X, Weikum ER, Tilo D, Vinson C, Ortlund EA. Liu X, et al. Nucleic Acids Res. 2021 Sep 7;49(15):8923-8933. doi: 10.1093/nar/gkab605. Nucleic Acids Res. 2021. PMID: 34289059 Free PMC article.

10

Structural insights into glucocorticoid receptor function.

Frank F, Ortlund EA, Liu X. Frank F, et al. Among authors: liu x. Biochem Soc Trans. 2021 Nov 1;49(5):2333-2343. doi: 10.1042/BST20210419. Biochem Soc Trans. 2021. PMID: 34709368 Free PMC article. Review.

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