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Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathway.
Wehling-Henricks M, Welc SS, Samengo G, Rinaldi C, Lindsey C, Wang Y, Lee J, Kuro-O M, Tidball JG. Wehling-Henricks M, et al. Among authors: wang y. Hum Mol Genet. 2018 Jan 1;27(1):14-29. doi: 10.1093/hmg/ddx380. Hum Mol Genet. 2018. PMID: 29040534 Free PMC article.
Aging of the immune system causes reductions in muscle stem cell populations, promotes their shift to a fibrogenic phenotype, and modulates sarcopenia.
Wang Y, Wehling-Henricks M, Welc SS, Fisher AL, Zuo Q, Tidball JG. Wang Y, et al. FASEB J. 2019 Jan;33(1):1415-1427. doi: 10.1096/fj.201800973R. Epub 2018 Aug 21. FASEB J. 2019. PMID: 30130434 Free PMC article.
Together, our results demonstrate that aging of bone marrow cells promotes the age-related reduction of satellite cell number and function and contributes to sarcopenia.-Wang, Y., Wehling-Henricks, M., Welc, S. S., Fisher, A. L., Zuo, Q., Tidball, J. G. Aging of the …
Together, our results demonstrate that aging of bone marrow cells promotes the age-related reduction of satellite cell number and function a …
298,067 results
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