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52 results

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Page 1
Immune Imprinting Drives Human Norovirus Potential for Global Spread.
Lindesmith LC, Boshier FAT, Brewer-Jensen PD, Roy S, Costantini V, Mallory ML, Zweigart M, May SR, Conrad H, O'Reilly KM, Kelly D, Celma CC, Beard S, Williams R, Tutill HJ, Becker Dreps S, Bucardo F, Allen DJ, Vinjé J, Goldstein RA, Breuer J, Baric RS. Lindesmith LC, et al. Among authors: may sr. mBio. 2022 Oct 26;13(5):e0186122. doi: 10.1128/mbio.01861-22. Epub 2022 Sep 14. mBio. 2022. PMID: 36102514 Free PMC article.
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice.
Schäfer A, Martinez DR, Won JJ, Meganck RM, Moreira FR, Brown AJ, Gully KL, Zweigart MR, Conrad WS, May SR, Dong S, Kalla R, Chun K, Du Pont V, Babusis D, Tang J, Murakami E, Subramanian R, Barrett KT, Bleier BJ, Bannister R, Feng JY, Bilello JP, Cihlar T, Mackman RL, Montgomery SA, Baric RS, Sheahan TP. Schäfer A, et al. Among authors: may sr. Sci Transl Med. 2022 May 4;14(643):eabm3410. doi: 10.1126/scitranslmed.abm3410. Epub 2022 May 4. Sci Transl Med. 2022. PMID: 35315683 Free PMC article.
Antigenic Site Immunodominance Redirection Following Repeat Variant Exposure.
Lindesmith LC, Brewer-Jensen PD, Mallory ML, Zweigart MR, May SR, Kelly D, Williams R, Becker-Dreps S, Bucardo F, Allen DJ, Breuer J, Baric RS. Lindesmith LC, et al. Among authors: may sr. Viruses. 2022 Jun 14;14(6):1293. doi: 10.3390/v14061293. Viruses. 2022. PMID: 35746763 Free PMC article.
A Multitrait Locus Regulates Sarbecovirus Pathogenesis.
Schäfer A, Leist SR, Gralinski LE, Martinez DR, Winkler ES, Okuda K, Hawkins PE, Gully KL, Graham RL, Scobey DT, Bell TA, Hock P, Shaw GD, Loome JF, Madden EA, Anderson E, Baxter VK, Taft-Benz SA, Zweigart MR, May SR, Dong S, Clark M, Miller DR, Lynch RM, Heise MT, Tisch R, Boucher RC, Pardo Manuel de Villena F, Montgomery SA, Diamond MS, Ferris MT, Baric RS. Schäfer A, et al. Among authors: may sr. mBio. 2022 Aug 30;13(4):e0145422. doi: 10.1128/mbio.01454-22. Epub 2022 Jul 12. mBio. 2022. PMID: 35862771 Free PMC article.
Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential.
Martinez DR, Moreira FR, Zweigart MR, Gully KL, De la Cruz G, Brown AJ, Adams LE, Catanzaro N, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, Scobey DT, Montgomery SA, Perry J, Babusis D, Barrett KT, Nguyen AH, Nguyen AQ, Kalla R, Bannister R, Bilello JP, Feng JY, Cihlar T, Baric RS, Mackman RL, Schäfer A, Sheahan TP. Martinez DR, et al. Among authors: may sr. bioRxiv [Preprint]. 2023 Jun 28:2023.06.27.546784. doi: 10.1101/2023.06.27.546784. bioRxiv. 2023. Update in: Sci Transl Med. 2024 May 22;16(748):eadj4504. doi: 10.1126/scitranslmed.adj4504 PMID: 37425890 Free PMC article. Updated. Preprint.
Infant antibody and B-cell responses following confirmed pediatric GII.17 norovirus infections functionally distinguish GII.17 genetic clusters.
Strother CA, Brewer-Jensen PD, Becker-Dreps S, Zepeda O, May S, Gonzalez F, Reyes Y, McElvany BD, Averill AM, Mallory ML, Montmayeur AM, Costantini VP, Vinjé J, Baric RS, Bucardo F, Lindesmith LC, Diehl SA. Strother CA, et al. Front Immunol. 2023 Aug 18;14:1229724. doi: 10.3389/fimmu.2023.1229724. eCollection 2023. Front Immunol. 2023. PMID: 37662930 Free PMC article.
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses.
Martinez DR, Moreira FR, Catanzaro NJ, Diefenbacher MV, Zweigart MR, Gully KL, De la Cruz G, Brown AJ, Adams LE, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, Scobey DT, Nguyen C, Montgomery SA, Perry JK, Babusis D, Barrett KT, Nguyen AH, Nguyen AQ, Kalla R, Bannister R, Feng JY, Cihlar T, Baric RS, Mackman RL, Bilello JP, Schäfer A, Sheahan TP. Martinez DR, et al. Among authors: may sr. Sci Transl Med. 2024 May 22;16(748):eadj4504. doi: 10.1126/scitranslmed.adj4504. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38776389 Free PMC article.
Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection.
Atochina-Vasserman EN, Lindesmith LC, Mirabelli C, Ona NA, Reagan EK, Brewer-Jensen PD, Mercado-Lopez X, Shahnawaz H, Meshanni JA, Baboo I, Mallory ML, Zweigart MR, May SR, Mui BL, Tam YK, Wobus CE, Baric RS, Weissman D. Atochina-Vasserman EN, et al. Among authors: may sr. NPJ Vaccines. 2024 Oct 1;9(1):182. doi: 10.1038/s41541-024-00976-z. NPJ Vaccines. 2024. PMID: 39353926 Free PMC article.
A Multitrait Locus Regulates Sarbecovirus Pathogenesis.
Schäfer A, Leist SR, Gralinski LE, Martinez DR, Winkler ES, Okuda K, Hawkins PE, Gully KL, Graham RL, Scobey DT, Bell TA, Hock P, Shaw GD, Loome JF, Madden EA, Anderson E, Baxter VK, Taft-Benz SA, Zweigart MR, May SR, Dong S, Clark M, Miller DR, Lynch RM, Heise MT, Tisch R, Boucher RC, Pardo Manuel de Villena F, Montgomery SA, Diamond MS, Ferris MT, Baric RS. Schäfer A, et al. Among authors: may sr. bioRxiv [Preprint]. 2022 Jun 2:2022.06.01.494461. doi: 10.1101/2022.06.01.494461. bioRxiv. 2022. Update in: mBio. 2022 Aug 30;13(4):e0145422. doi: 10.1128/mbio.01454-22 PMID: 35677067 Free PMC article. Updated. Preprint.
52 results