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Structures of α-synuclein filaments from human brains with Lewy pathology.
Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M. Yang Y, et al. Among authors: hasegawa k, hasegawa m. Nature. 2022 Oct;610(7933):791-795. doi: 10.1038/s41586-022-05319-3. Epub 2022 Sep 15. Nature. 2022. PMID: 36108674 Free PMC article.
alpha-Synuclein is phosphorylated in synucleinopathy lesions.
Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T. Fujiwara H, et al. Among authors: hasegawa m. Nat Cell Biol. 2002 Feb;4(2):160-4. doi: 10.1038/ncb748. Nat Cell Biol. 2002. PMID: 11813001
Accumulation of phosphorylated alpha-synuclein in aging human brain.
Saito Y, Kawashima A, Ruberu NN, Fujiwara H, Koyama S, Sawabe M, Arai T, Nagura H, Yamanouchi H, Hasegawa M, Iwatsubo T, Murayama S. Saito Y, et al. Among authors: hasegawa m. J Neuropathol Exp Neurol. 2003 Jun;62(6):644-54. doi: 10.1093/jnen/62.6.644. J Neuropathol Exp Neurol. 2003. PMID: 12834109
Unique tauopathy in Fukuyama-type congenital muscular dystrophy.
Saito Y, Motoyoshi Y, Kashima T, Izumiyama-Shimomura N, Toda T, Nakano I, Hasegawa M, Murayama S. Saito Y, et al. Among authors: hasegawa m. J Neuropathol Exp Neurol. 2005 Dec;64(12):1118-26. doi: 10.1097/01.jnen.0000190069.10633.c2. J Neuropathol Exp Neurol. 2005. PMID: 16319722
Small molecule inhibitors of alpha-synuclein filament assembly.
Masuda M, Suzuki N, Taniguchi S, Oikawa T, Nonaka T, Iwatsubo T, Hisanaga S, Goedert M, Hasegawa M. Masuda M, et al. Among authors: hasegawa m. Biochemistry. 2006 May 16;45(19):6085-94. doi: 10.1021/bi0600749. Biochemistry. 2006. PMID: 16681381
4,209 results