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GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinoma.
de Andrés MP, Jackson RJ, Felipe I, Zagorac S, Pilarsky C, Schlitter AM, Martinez de Villareal J, Jang GH, Costello E, Gallinger S, Ghaneh P, Greenhalf W, Knösel T, Palmer DH, Ruemmele P, Weichert W, Buechler M, Hackert T, Neoptolemos JP, Notta F, Malats N, Martinelli P, Real FX. de Andrés MP, et al. Among authors: knosel t. Gut. 2023 Mar;72(3):535-548. doi: 10.1136/gutjnl-2021-325803. Epub 2022 Sep 15. Gut. 2023. PMID: 36109153
Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes.
Winter C, Kristiansen G, Kersting S, Roy J, Aust D, Knösel T, Rümmele P, Jahnke B, Hentrich V, Rückert F, Niedergethmann M, Weichert W, Bahra M, Schlitt HJ, Settmacher U, Friess H, Büchler M, Saeger HD, Schroeder M, Pilarsky C, Grützmann R. Winter C, et al. Among authors: knosel t. PLoS Comput Biol. 2012;8(5):e1002511. doi: 10.1371/journal.pcbi.1002511. Epub 2012 May 17. PLoS Comput Biol. 2012. PMID: 22615549 Free PMC article.
STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma.
Evers L, Perez-Mancera PA, Lenkiewicz E, Tang N, Aust D, Knösel T, Rümmele P, Holley T, Kassner M, Aziz M, Ramanathan RK, Von Hoff DD, Yin H, Pilarsky C, Barrett MT. Evers L, et al. Among authors: knosel t. Genome Med. 2014 Jan 31;6(1):9. doi: 10.1186/gm526. eCollection 2014. Genome Med. 2014. PMID: 24484537 Free PMC article.
Cytosolic 5'-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites.
Patzak MS, Kari V, Patil S, Hamdan FH, Goetze RG, Brunner M, Gaedcke J, Kitz J, Jodrell DI, Richards FM, Pilarsky C, Gruetzmann R, Rümmele P, Knösel T, Hessmann E, Ellenrieder V, Johnsen SA, Neesse A. Patzak MS, et al. Among authors: knosel t. EBioMedicine. 2019 Feb;40:394-405. doi: 10.1016/j.ebiom.2019.01.037. Epub 2019 Jan 30. EBioMedicine. 2019. PMID: 30709769 Free PMC article.
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.
Bermejo-Rodriguez C, Araos Henríquez J, Caligiuri G, Pinto Teles S, Park Y, Evans A, Barrera LN, Neesse A, Grützmann R, Aust D, Rümmele P, Knösel T, Narita M, Narita M, Campbell F, Öhlund D, Pilarsky C, Dow LE, Humbert PO, Biffi G, Tuveson DA, Perez-Mancera PA. Bermejo-Rodriguez C, et al. Among authors: knosel t. Cancer Res. 2024 Sep 16;84(18):2968-2984. doi: 10.1158/0008-5472.CAN-23-3419. Cancer Res. 2024. PMID: 39037766
Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer.
Dreyer SB, Pinese M, Jamieson NB, Scarlett CJ, Colvin EK, Pajic M, Johns AL, Humphris JL, Wu J, Cowley MJ, Chou A, Nagrial AM, Chantrill L, Chin VT, Jones MD, Moran-Jones K, Carter CR, Dickson EJ, Samra JS, Merrett ND, Gill AJ, Kench JG, Duthie F, Miller DK, Cooke S, Aust D, Knösel T, Rümmele P, Grützmann R, Pilarsky C, Nguyen NQ, Musgrove EA, Bailey PJ, McKay CJ, Biankin AV, Chang DK; Australian Pancreatic Cancer Genome Initiative; Glasgow Precision Oncology Laboratory. Dreyer SB, et al. Among authors: knosel t. Ann Surg. 2020 Aug;272(2):366-376. doi: 10.1097/SLA.0000000000003143. Ann Surg. 2020. PMID: 32675551 Free PMC article.
193 results