Adedeji AO - Search Results

1

Nonclinical Pharmacokinetics, Pharmacodynamics, and Translational Model of RO7297089, A Novel Anti-BCMA/CD16A Bispecific Tetravalent Antibody for the Treatment of Multiple Myeloma.

Cai H, Kakiuchi-Kiyota S, Hendricks R, Zhong S, Liu L, Adedeji AO, Chan P, Schutten MM, Kamath AV, Ovacik MA. Cai H, et al. Among authors: adedeji ao. AAPS J. 2022 Sep 20;24(6):100. doi: 10.1208/s12248-022-00744-8. AAPS J. 2022. PMID: 36127472

2

A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys.

Mitra MS, Lancaster K, Adedeji AO, Palanisamy GS, Dave RA, Zhong F, Holdren MS, Turley SJ, Liang WC, Wu Y, Meng YG, Vernes JM, Schutten MM. Mitra MS, et al. Among authors: adedeji ao. Toxicol Sci. 2020 May 1;175(1):24-34. doi: 10.1093/toxsci/kfaa024. Toxicol Sci. 2020. PMID: 32077954

3

A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma.

Kakiuchi-Kiyota S, Ross T, Wallweber HA, Kiefer JR, Schutten MM, Adedeji AO, Cai H, Hendricks R, Cohen S, Myneni S, Liu L, Fullerton A, Corr N, Yu L, de Almeida Nagata D, Zhong S, Leong SR, Li J, Nakamura R, Sumiyoshi T, Li J, Ovacik AM, Zheng B, Dillon M, Spiess C, Wingert S, Rajkovic E, Ellwanger K, Reusch U, Polson AG. Kakiuchi-Kiyota S, et al. Among authors: adedeji ao. Leukemia. 2022 Apr;36(4):1006-1014. doi: 10.1038/s41375-021-01478-w. Epub 2022 Jan 10. Leukemia. 2022. PMID: 35001074

4

Reduced Fasting Duration in Cynomolgus Monkeys Enhances Animal Welfare During Toxicology Studies.

Adedeji AO, Pourmohamad T, Tripathi N, Zhong S, Degner KR, Zhong F, Sangaraju D, Williams K, Dybdal N. Adedeji AO, et al. Toxicol Pathol. 2023 Jul;51(5):264-277. doi: 10.1177/01926233231193395. Epub 2023 Sep 13. Toxicol Pathol. 2023. PMID: 37702042 Free PMC article.

5

Neutropenia in Cynomolgus Monkeys With Anti-Drug Antibodies Associated With Administration of Afucosylated Humanized Monoclonal Antibodies.

Adedeji AO, Zhong F, Getz JA, Zhong Z, Halpern W. Adedeji AO, et al. Toxicol Pathol. 2022 Dec;50(8):910-919. doi: 10.1177/01926233221131510. Epub 2022 Nov 3. Toxicol Pathol. 2022. PMID: 36329562 Free PMC article.

6

Atypical presentation and pathogenesis of a macaque lymphocryptoviral-associated B-cell lymphoma in a cynomolgus monkey.

Adedeji AO, Vemireddi V, Tripathi N, Durinck S, Maher JM, Vucic D, Halpern W. Adedeji AO, et al. Vet Clin Pathol. 2020 Mar;49(1):130-136. doi: 10.1111/vcp.12822. Epub 2020 Feb 3. Vet Clin Pathol. 2020. PMID: 32009251

7

Zoledronic acid and ibandronate-induced nephrotoxicity in 2D and 3D proximal tubule cells derived from human and rat.

Valencia LJ, Tseng M, Chu ML, Yu L, Adedeji AO, Kiyota T. Valencia LJ, et al. Among authors: adedeji ao. Toxicol Sci. 2024 Feb 28;198(1):86-100. doi: 10.1093/toxsci/kfad123. Toxicol Sci. 2024. PMID: 38059598

8

The Utility of Novel Urinary Biomarkers in Mice for Drug Development Studies.

Adedeji AO, Gu YZ, Pourmohamad T, Kanerva J, Chen Y, Atabakhsh E, Tackett MR, Chen F, Bhatt B, Gury T, Dorchies O, Sonee M, Morgan M, Burkey J, Gautier JC, McDuffie JE. Adedeji AO, et al. Int J Toxicol. 2021 Jan-Feb;40(1):15-25. doi: 10.1177/1091581820970498. Epub 2020 Nov 9. Int J Toxicol. 2021. PMID: 33161787

9

Scientific and Regulatory Policy Committee Points to Consider: Integration of Clinical Pathology Data With Anatomic Pathology Data in Nonclinical Toxicology Studies.

Siska W, Schultze AE, Ennulat D, Biddle K, Logan M, Adedeji AO, Arndt T, Aulbach AD. Siska W, et al. Among authors: adedeji ao. Toxicol Pathol. 2022 Aug;50(6):808-826. doi: 10.1177/01926233221108887. Epub 2022 Aug 17. Toxicol Pathol. 2022. PMID: 35852467

10

Investigating the Value of Urine Volume, Creatinine, and Cystatin C for Urinary Biomarkers Normalization for Drug Development Studies.

Adedeji AO, Pourmohamad T, Chen Y, Burkey J, Betts CJ, Bickerton SJ, Sonee M, McDuffie JE. Adedeji AO, et al. Int J Toxicol. 2019 Jan/Feb;38(1):12-22. doi: 10.1177/1091581818819791. Epub 2019 Jan 23. Int J Toxicol. 2019. PMID: 30673360

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