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Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders.
El Andari J, Renaud-Gabardos E, Tulalamba W, Weinmann J, Mangin L, Pham QH, Hille S, Bennett A, Attebi E, Bourges E, Leborgne C, Guerchet N, Fakhiri J, Krämer C, Wiedtke E, McKenna R, Guianvarc'h L, Toueille M, Ronzitti G, Hebben M, Mingozzi F, VandenDriessche T, Agbandje-McKenna M, Müller OJ, Chuah MK, Buj-Bello A, Grimm D. El Andari J, et al. Among authors: grimm d. Sci Adv. 2022 Sep 23;8(38):eabn4704. doi: 10.1126/sciadv.abn4704. Epub 2022 Sep 21. Sci Adv. 2022. PMID: 36129972 Free PMC article.
Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines.
Börner K, Niopek D, Cotugno G, Kaldenbach M, Pankert T, Willemsen J, Zhang X, Schürmann N, Mockenhaupt S, Serva A, Hiet MS, Wiedtke E, Castoldi M, Starkuviene V, Erfle H, Gilbert DF, Bartenschlager R, Boutros M, Binder M, Streetz K, Kräusslich HG, Grimm D. Börner K, et al. Among authors: grimm d. Nucleic Acids Res. 2013 Nov;41(21):e199. doi: 10.1093/nar/gkt836. Epub 2013 Sep 17. Nucleic Acids Res. 2013. PMID: 24049077 Free PMC article.
A chemical switch for controlling viral infectivity.
Hörner M, Kaufmann B, Cotugno G, Wiedtke E, Büning H, Grimm D, Weber W. Hörner M, et al. Among authors: grimm d. Chem Commun (Camb). 2014 Sep 14;50(71):10319-22. doi: 10.1039/c4cc03292f. Chem Commun (Camb). 2014. PMID: 25058661
770 results