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Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function.
Brunet-Ratnasingham E, Morou A, Dubé M, Niessl J, Baxter AE, Tastet O, Brassard N, Ortega-Delgado G, Charlebois R, Freeman GJ, Tremblay C, Routy JP, Kaufmann DE. Brunet-Ratnasingham E, et al. Among authors: brassard n. EBioMedicine. 2022 Oct;84:104254. doi: 10.1016/j.ebiom.2022.104254. Epub 2022 Sep 20. EBioMedicine. 2022. PMID: 36150362 Free PMC article.
CD4 mimetics sensitize HIV-1-infected cells to ADCC.
Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy JP, Smith AB 3rd, Park J, Jones DM, Courter JR, Melillo BN, Kaufmann DE, Hahn BH, Permar SR, Haynes BF, Madani N, Sodroski JG, Finzi A. Richard J, et al. Among authors: brassard n. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94. doi: 10.1073/pnas.1506755112. Epub 2015 May 4. Proc Natl Acad Sci U S A. 2015. PMID: 25941367 Free PMC article.
Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity.
Richard J, Veillette M, Ding S, Zoubchenok D, Alsahafi N, Coutu M, Brassard N, Park J, Courter JR, Melillo B, Smith AB 3rd, Shaw GM, Hahn BH, Sodroski J, Kaufmann DE, Finzi A. Richard J, et al. Among authors: brassard n. EBioMedicine. 2015 Dec 9;3:122-134. doi: 10.1016/j.ebiom.2015.12.004. eCollection 2016 Jan. EBioMedicine. 2015. PMID: 26870823 Free PMC article.
Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.
Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Charlebois R, Massanella M, Brassard N, Alsahafi N, Delgado GG, Routy JP, Walker BD, Finzi A, Chomont N, Kaufmann DE. Baxter AE, et al. Among authors: brassard n. Cell Host Microbe. 2016 Sep 14;20(3):368-380. doi: 10.1016/j.chom.2016.07.015. Epub 2016 Aug 18. Cell Host Microbe. 2016. PMID: 27545045 Free PMC article.
Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A. Richard J, et al. Among authors: brassard n. EBioMedicine. 2016 Oct;12:208-218. doi: 10.1016/j.ebiom.2016.09.004. Epub 2016 Sep 9. EBioMedicine. 2016. PMID: 27633463 Free PMC article.
Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.
Prévost J, Zoubchenok D, Richard J, Veillette M, Pacheco B, Coutu M, Brassard N, Parsons MS, Ruxrungtham K, Bunupuradah T, Tovanabutra S, Hwang KK, Moody MA, Haynes BF, Bonsignori M, Sodroski J, Kaufmann DE, Shaw GM, Chenine AL, Finzi A. Prévost J, et al. Among authors: brassard n. J Virol. 2017 Mar 13;91(7):e02452-16. doi: 10.1128/JVI.02452-16. Print 2017 Apr 1. J Virol. 2017. PMID: 28100618 Free PMC article.
BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.
Richard J, Prévost J, von Bredow B, Ding S, Brassard N, Medjahed H, Coutu M, Melillo B, Bibollet-Ruche F, Hahn BH, Kaufmann DE, Smith AB 3rd, Sodroski J, Sauter D, Kirchhoff F, Gee K, Neil SJ, Evans DT, Finzi A. Richard J, et al. Among authors: brassard n. J Virol. 2017 May 12;91(11):e00219-17. doi: 10.1128/JVI.00219-17. Print 2017 Jun 1. J Virol. 2017. PMID: 28331088 Free PMC article.
69 results