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Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Najjar A, Punt A, Wambaugh J, Paini A, Ellison C, Fragki S, Bianchi E, Zhang F, Westerhout J, Mueller D, Li H, Shi Q, Gant TW, Botham P, Bars R, Piersma A, van Ravenzwaay B, Kramer NI. Najjar A, et al. Among authors: paini a. Arch Toxicol. 2022 Dec;96(12):3407-3419. doi: 10.1007/s00204-022-03356-5. Epub 2022 Sep 5. Arch Toxicol. 2022. PMID: 36063173 Free PMC article.
Towards a systematic use of effect biomarkers in population and occupational biomonitoring.
Zare Jeddi M, Hopf NB, Viegas S, Price AB, Paini A, van Thriel C, Benfenati E, Ndaw S, Bessems J, Behnisch PA, Leng G, Duca RC, Verhagen H, Cubadda F, Brennan L, Ali I, David A, Mustieles V, Fernandez MF, Louro H, Pasanen-Kase R. Zare Jeddi M, et al. Among authors: paini a. Environ Int. 2021 Jan;146:106257. doi: 10.1016/j.envint.2020.106257. Epub 2020 Dec 15. Environ Int. 2021. PMID: 33395925 Free article. Review.
Predicting nonlinear relationships between external and internal concentrations with physiologically based pharmacokinetic modeling.
Hoer D, Barton HA, Paini A, Bartels M, Ingle B, Domoradzki J, Fisher J, Embry M, Villanueva P, Miller D, Nguyen J, Zhang Q, Edwards SW, Tan YM. Hoer D, et al. Among authors: paini a. Toxicol Appl Pharmacol. 2022 Apr 1;440:115922. doi: 10.1016/j.taap.2022.115922. Epub 2022 Feb 15. Toxicol Appl Pharmacol. 2022. PMID: 35176293 Free PMC article.
Automated workflows for modelling chemical fate, kinetics and toxicity.
Sala Benito JV, Paini A, Richarz AN, Meinl T, Berthold MR, Cronin MTD, Worth AP. Sala Benito JV, et al. Among authors: paini a. Toxicol In Vitro. 2017 Dec;45(Pt 2):249-257. doi: 10.1016/j.tiv.2017.03.004. Epub 2017 Mar 18. Toxicol In Vitro. 2017. PMID: 28323105 Free PMC article.
185 results