Dementiev AA - Search Results

1

Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists.

Irwin S, Karr C, Furman C, Tsai J, Gee P, Banka D, Wibowo AS, Dementiev AA, O'Shea M, Yang J, Lowe J, Mitchell L, Ruppel S, Fekkes P, Zhu P, Korpal M, Larsen NA. Irwin S, et al. Among authors: dementiev aa. J Biol Chem. 2022 Nov;298(11):102539. doi: 10.1016/j.jbc.2022.102539. Epub 2022 Sep 28. J Biol Chem. 2022. PMID: 36179791 Free PMC article.

2

Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.

Huang X, Dementiev A, Olson ST, Gettins PG. Huang X, et al. J Biol Chem. 2010 Jun 25;285(26):20399-409. doi: 10.1074/jbc.M110.112748. Epub 2010 Apr 28. J Biol Chem. 2010. PMID: 20427285 Free PMC article.

3

The allosteric mechanism of activation of antithrombin as an inhibitor of factor IXa and factor Xa: heparin-independent full activation through mutations adjacent to helix D.

Dementiev A, Swanson R, Roth R, Isetti G, Izaguirre G, Olson ST, Gettins PGW. Dementiev A, et al. J Biol Chem. 2013 Nov 22;288(47):33611-33619. doi: 10.1074/jbc.M113.510727. Epub 2013 Sep 25. J Biol Chem. 2013. PMID: 24068708 Free PMC article.

4

Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases.

Dementiev A, Simonovic M, Volz K, Gettins PG. Dementiev A, et al. J Biol Chem. 2003 Sep 26;278(39):37881-7. doi: 10.1074/jbc.M305195200. Epub 2003 Jul 14. J Biol Chem. 2003. PMID: 12860985 Free article.

5

The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity.

Dementiev A, Petitou M, Herbert JM, Gettins PG. Dementiev A, et al. Nat Struct Mol Biol. 2004 Sep;11(9):863-7. doi: 10.1038/nsmb810. Epub 2004 Aug 15. Nat Struct Mol Biol. 2004. PMID: 15311268

6

Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase.

Dementiev A, Dobó J, Gettins PG. Dementiev A, et al. J Biol Chem. 2006 Feb 10;281(6):3452-7. doi: 10.1074/jbc.M510564200. Epub 2005 Dec 1. J Biol Chem. 2006. PMID: 16321984 Free article.

7

Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur.

Dementiev A, Joachimiak A, Nguyen H, Gorelik A, Illes K, Shabani S, Gelsomino M, Ahn EE, Nagar B, Doan N. Dementiev A, et al. J Med Chem. 2019 Jan 24;62(2):987-992. doi: 10.1021/acs.jmedchem.8b01723. Epub 2018 Dec 19. J Med Chem. 2019. PMID: 30525581 Free PMC article.

8

K-Ras4B lipoprotein synthesis: biochemical characterization, functional properties, and dimer formation.

Dementiev A. Dementiev A. Protein Expr Purif. 2012 Jul;84(1):86-93. doi: 10.1016/j.pep.2012.04.021. Epub 2012 May 5. Protein Expr Purif. 2012. PMID: 22569482

9

Structures of human plasma β-factor XIIa cocrystallized with potent inhibitors.

Dementiev A, Silva A, Yee C, Li Z, Flavin MT, Sham H, Partridge JR. Dementiev A, et al. Blood Adv. 2018 Mar 13;2(5):549-558. doi: 10.1182/bloodadvances.2018016337. Blood Adv. 2018. PMID: 29519898 Free PMC article.

10

High resolution crystal structure of the FAK FERM domain reveals new insights on the Druggability of tyrosine 397 and the Src SH3 binding site.

Marlowe T, Dementiev A, Figel S, Rivera A, Flavin M, Cance W. Marlowe T, et al. BMC Mol Cell Biol. 2019 May 20;20(1):10. doi: 10.1186/s12860-019-0193-4. BMC Mol Cell Biol. 2019. PMID: 31109284 Free PMC article.

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