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Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease.
Minter MR, Hinterleitner R, Meisel M, Zhang C, Leone V, Zhang X, Oyler-Castrillo P, Zhang X, Musch MW, Shen X, Jabri B, Chang EB, Tanzi RE, Sisodia SS. Minter MR, et al. Among authors: sisodia ss. Sci Rep. 2017 Sep 5;7(1):10411. doi: 10.1038/s41598-017-11047-w. Sci Rep. 2017. PMID: 28874832 Free PMC article.
Gut microbiota-driven brain Aβ amyloidosis in mice requires microglia.
Dodiya HB, Lutz HL, Weigle IQ, Patel P, Michalkiewicz J, Roman-Santiago CJ, Zhang CM, Liang Y, Srinath A, Zhang X, Xia J, Olszewski M, Zhang X, Schipma MJ, Chang EB, Tanzi RE, Gilbert JA, Sisodia SS. Dodiya HB, et al. Among authors: sisodia ss. J Exp Med. 2022 Jan 3;219(1):e20200895. doi: 10.1084/jem.20200895. Epub 2021 Dec 2. J Exp Med. 2022. PMID: 34854884 Free PMC article.
ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.
Seo DO, O'Donnell D, Jain N, Ulrich JD, Herz J, Li Y, Lemieux M, Cheng J, Hu H, Serrano JR, Bao X, Franke E, Karlsson M, Meier M, Deng S, Desai C, Dodiya H, Lelwala-Guruge J, Handley SA, Kipnis J, Sisodia SS, Gordon JI, Holtzman DM. Seo DO, et al. Among authors: sisodia ss. Science. 2023 Jan 13;379(6628):eadd1236. doi: 10.1126/science.add1236. Epub 2023 Jan 13. Science. 2023. PMID: 36634180 Free PMC article.
Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
Bosch ME, Dodiya HB, Michalkiewicz J, Lee C, Shaik SM, Weigle IQ, Zhang C, Osborn J, Nambiar A, Patel P, Parhizkar S, Zhang X, Laury ML, Mondal P, Gomm A, Schipma MJ, Mallah D, Butovsky O, Chang EB, Tanzi RE, Gilbert JA, Holtzman DM, Sisodia SS. Bosch ME, et al. Among authors: sisodia ss. Mol Neurodegener. 2024 Feb 17;19(1):18. doi: 10.1186/s13024-023-00700-w. Mol Neurodegener. 2024. PMID: 38365827 Free PMC article.
235 results