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SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Gui M, Croft JT, Zabeo D, Acharya V, Kollman JM, Burgoyne T, Höög JL, Brown A. Gui M, et al. Among authors: brown a. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2207605119. doi: 10.1073/pnas.2207605119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191189 Free PMC article.
Structure of the Decorated Ciliary Doublet Microtubule.
Ma M, Stoyanova M, Rademacher G, Dutcher SK, Brown A, Zhang R. Ma M, et al. Among authors: brown a. Cell. 2019 Oct 31;179(4):909-922.e12. doi: 10.1016/j.cell.2019.09.030. Epub 2019 Oct 24. Cell. 2019. PMID: 31668805 Free PMC article.
Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Zhang M, Gui M, Wang ZF, Gorgulla C, Yu JJ, Wu H, Sun ZJ, Klenk C, Merklinger L, Morstein L, Hagn F, Plückthun A, Brown A, Nasr ML, Wagner G. Zhang M, et al. Among authors: brown a. Nat Struct Mol Biol. 2021 Mar;28(3):258-267. doi: 10.1038/s41594-020-00554-6. Epub 2021 Feb 25. Nat Struct Mol Biol. 2021. PMID: 33633398 Free PMC article.
De novo identification of mammalian ciliary motility proteins using cryo-EM.
Gui M, Farley H, Anujan P, Anderson JR, Maxwell DW, Whitchurch JB, Botsch JJ, Qiu T, Meleppattu S, Singh SK, Zhang Q, Thompson J, Lucas JS, Bingle CD, Norris DP, Roy S, Brown A. Gui M, et al. Among authors: brown a. Cell. 2021 Nov 11;184(23):5791-5806.e19. doi: 10.1016/j.cell.2021.10.007. Epub 2021 Oct 28. Cell. 2021. PMID: 34715025 Free PMC article.
Axonemal structures reveal mechanoregulatory and disease mechanisms.
Walton T, Gui M, Velkova S, Fassad MR, Hirst RA, Haarman E, O'Callaghan C, Bottier M, Burgoyne T, Mitchison HM, Brown A. Walton T, et al. Among authors: brown a. Nature. 2023 Jun;618(7965):625-633. doi: 10.1038/s41586-023-06140-2. Epub 2023 May 31. Nature. 2023. PMID: 37258679 Free PMC article.
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