Ravikumar B - Search Results

1

Pharmacological mTOR-inhibition facilitates clearance of AD-related tau aggregates in the mouse brain.

Morawe MP, Liao F, Amberg W, van Bergeijk J, Chang R, Gulino M, Hamilton C, Hoft C, Lumpkin C, Mastis B, McGlame E, Nuber J, Plaas C, Ravikumar B, Roy K, Schanzenbächer M, Tierno J, Lakics V, Dellovade T, Townsend M. Morawe MP, et al. Among authors: ravikumar b. Eur J Pharmacol. 2022 Nov 5;934:175301. doi: 10.1016/j.ejphar.2022.175301. Epub 2022 Sep 30. Eur J Pharmacol. 2022. PMID: 36191631 Free article.

2

Arrayed CRISPR reveals genetic regulators of tau aggregation, autophagy and mitochondria in Alzheimer's disease model.

Duan L, Hu M, Tamm JA, Grinberg YY, Shen F, Chai Y, Xi H, Gibilisco L, Ravikumar B, Gautam V, Karran E, Townsend M, Talanian RV. Duan L, et al. Among authors: ravikumar b. Sci Rep. 2021 Feb 3;11(1):2879. doi: 10.1038/s41598-021-82658-7. Sci Rep. 2021. PMID: 33536571 Free PMC article.

3

Differential efficacy of the TSPO ligands etifoxine and XBD-173 in two rodent models of Multiple Sclerosis.

Ravikumar B, Crawford D, Dellovade T, Savinainen A, Graham D, Liere P, Oudinet JP, Webb M, Hering H. Ravikumar B, et al. Neuropharmacology. 2016 Sep;108:229-37. doi: 10.1016/j.neuropharm.2016.03.053. Epub 2016 Mar 30. Neuropharmacology. 2016. PMID: 27039042

4

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, Oroz LG, Scaravilli F, Easton DF, Duden R, O'Kane CJ, Rubinsztein DC. Ravikumar B, et al. Nat Genet. 2004 Jun;36(6):585-95. doi: 10.1038/ng1362. Epub 2004 May 16. Nat Genet. 2004. PMID: 15146184

5

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies.

Sarkar S, Ravikumar B, Floto RA, Rubinsztein DC. Sarkar S, et al. Among authors: ravikumar b. Cell Death Differ. 2009 Jan;16(1):46-56. doi: 10.1038/cdd.2008.110. Epub 2008 Jul 18. Cell Death Differ. 2009. PMID: 18636076 Review.

6

Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications.

Williams A, Jahreiss L, Sarkar S, Saiki S, Menzies FM, Ravikumar B, Rubinsztein DC. Williams A, et al. Among authors: ravikumar b. Curr Top Dev Biol. 2006;76:89-101. doi: 10.1016/S0070-2153(06)76003-3. Curr Top Dev Biol. 2006. PMID: 17118264 Review.

7

Clearance of mutant aggregate-prone proteins by autophagy.

Ravikumar B, Sarkar S, Rubinsztein DC. Ravikumar B, et al. Methods Mol Biol. 2008;445:195-211. doi: 10.1007/978-1-59745-157-4_13. Methods Mol Biol. 2008. PMID: 18425452

8

Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

Sarkar S, Ravikumar B, Rubinsztein DC. Sarkar S, et al. Among authors: ravikumar b. Methods Enzymol. 2009;453:83-110. doi: 10.1016/S0076-6879(08)04005-6. Methods Enzymol. 2009. PMID: 19216903

9

Rapamycin alleviates toxicity of different aggregate-prone proteins.

Berger Z, Ravikumar B, Menzies FM, Oroz LG, Underwood BR, Pangalos MN, Schmitt I, Wullner U, Evert BO, O'Kane CJ, Rubinsztein DC. Berger Z, et al. Among authors: ravikumar b. Hum Mol Genet. 2006 Feb 1;15(3):433-42. doi: 10.1093/hmg/ddi458. Epub 2005 Dec 20. Hum Mol Genet. 2006. PMID: 16368705

10

Protective roles for induction of autophagy in multiple proteinopathies.

Menzies FM, Ravikumar B, Rubinsztein DC. Menzies FM, et al. Among authors: ravikumar b. Autophagy. 2006 Jul-Sep;2(3):224-5. doi: 10.4161/auto.2696. Epub 2006 Jul 10. Autophagy. 2006. PMID: 16874096 Review.

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