Tan J - Search Results

1

RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer.

Deng P, Wang Z, Chen J, Liu S, Yao X, Liu S, Liu L, Yu Z, Huang Y, Xiong Z, Xiao R, Gao J, Liang W, Chen J, Liu H, Hong JH, Chan JY, Guan P, Chen J, Wang Y, Yin J, Li J, Zheng M, Zhang C, Zhou P, Kang T, Teh BT, Yu Q, Zuo Z, Jiang Q, Liu J, Xiong Y, Xia X, Tan J. Deng P, et al. Among authors: tan j. J Clin Invest. 2022 Nov 15;132(22):e159628. doi: 10.1172/JCI159628. J Clin Invest. 2022. PMID: 36201246 Free PMC article.

2

Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells.

Tan J, Zhuang L, Leong HS, Iyer NG, Liu ET, Yu Q. Tan J, et al. Cancer Res. 2005 Oct 1;65(19):9012-20. doi: 10.1158/0008-5472.CAN-05-1226. Cancer Res. 2005. PMID: 16204075

3

Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.

Zhao Y, Tan J, Zhuang L, Jiang X, Liu ET, Yu Q. Zhao Y, et al. Among authors: tan j. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16090-5. doi: 10.1073/pnas.0505585102. Epub 2005 Oct 21. Proc Natl Acad Sci U S A. 2005. PMID: 16243973 Free PMC article.

4

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.

Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q. Tan J, et al. Among authors: tan pb. Genes Dev. 2007 May 1;21(9):1050-63. doi: 10.1101/gad.1524107. Epub 2007 Apr 16. Genes Dev. 2007. PMID: 17437993 Free PMC article.

5

B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.

Tan J, Lee PL, Li Z, Jiang X, Lim YC, Hooi SC, Yu Q. Tan J, et al. Cancer Cell. 2010 Nov 16;18(5):459-71. doi: 10.1016/j.ccr.2010.10.021. Cancer Cell. 2010. PMID: 21075311 Free article.

6

PDK1-driven Myc signaling regulates cellular response to mTOR inhibitors.

Tan J, Yu Q. Tan J, et al. Cell Cycle. 2011 Apr 1;10(7):1019-20. doi: 10.4161/cc.10.7.15163. Epub 2011 Apr 1. Cell Cycle. 2011. PMID: 21430441 No abstract available.

7

Molecular mechanisms of tumor resistance to PI3K-mTOR-targeted therapy.

Tan J, Yu Q. Tan J, et al. Chin J Cancer. 2013 Jul;32(7):376-9. doi: 10.5732/cjc.012.10287. Epub 2013 May 14. Chin J Cancer. 2013. PMID: 23668928 Free PMC article. Review.

8

PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.

Tan J, Li Z, Lee PL, Guan P, Aau MY, Lee ST, Feng M, Lim CZ, Lee EY, Wee ZN, Lim YC, Karuturi RK, Yu Q. Tan J, et al. Cancer Discov. 2013 Oct;3(10):1156-71. doi: 10.1158/2159-8290.CD-12-0595. Epub 2013 Jul 25. Cancer Discov. 2013. PMID: 23887393

9

Inhibition of placental growth factor in renal cell carcinoma.

Bessho H, Wong B, Huang D, Siew EY, Huang D, Tan J, Ong CK, Tan SY, Matsumoto K, Iwamura M, Teh BT. Bessho H, et al. Among authors: tan j, tan sy. Anticancer Res. 2015 Jan;35(1):531-41. Anticancer Res. 2015. PMID: 25550599

10

MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases.

Ng CC, Tan J, Ong CK, Lim WK, Rajasegaran V, Nasir ND, Lim JC, Thike AA, Salahuddin SA, Iqbal J, Busmanis I, Chong AP, Teh BT, Tan PH. Ng CC, et al. Among authors: tan j, tan ph. J Clin Pathol. 2015 Sep;68(9):685-91. doi: 10.1136/jclinpath-2015-202896. Epub 2015 May 27. J Clin Pathol. 2015. PMID: 26018969

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