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Blocking LAIR1 signaling in immune cells inhibits tumor development.
Xie J, Gui X, Deng M, Chen H, Chen Y, Liu X, Ku Z, Tan L, Huang R, He Y, Zhang B, Lewis C, Chen K, Xu L, Xu J, Huang T, Liao XC, Zhang N, An Z, Zhang CC. Xie J, et al. Among authors: chen k, chen h, chen y. Front Immunol. 2022 Sep 21;13:996026. doi: 10.3389/fimmu.2022.996026. eCollection 2022. Front Immunol. 2022. PMID: 36211388 Free PMC article.
LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.
Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, Wu G, Yu C, John S, Hirayasu K, Nguyen N, Liu X, Huang F, Li L, Deng H, Tang H, Sadek AH, Zhang L, Huang T, Zou Y, Chen B, Zhu H, Arase H, Xia N, Jiang Y, Collins R, You MJ, Homsi J, Unni N, Lewis C, Chen GQ, Fu YX, Liao XC, An Z, Zheng J, Zhang N, Zhang CC. Deng M, et al. Among authors: chen b, chen w, chen h, chen gq, chen y. Nature. 2018 Oct;562(7728):605-609. doi: 10.1038/s41586-018-0615-z. Epub 2018 Oct 17. Nature. 2018. PMID: 30333625 Free PMC article.
Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.
Gui X, Deng M, Song H, Chen Y, Xie J, Li Z, He L, Huang F, Xu Y, Anami Y, Yu H, Yu C, Li L, Yuan Z, Xu X, Wang Q, Chai Y, Huang T, Shi Y, Tsuchikama K, Liao XC, Xia N, Gao GF, Zhang N, Zhang CC, An Z. Gui X, et al. Among authors: chen y. Cancer Immunol Res. 2019 Aug;7(8):1244-1257. doi: 10.1158/2326-6066.CIR-19-0036. Epub 2019 Jun 18. Cancer Immunol Res. 2019. PMID: 31213474 Free PMC article.
Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection.
Ye X, Gui X, Freed DC, Ku Z, Li L, Chen Y, Xiong W, Fan X, Su H, He X, Rustandi RR, Loughney JW, Ma N, Espeseth AS, Liu J, Zhu H, Wang D, Zhang N, Fu TM, An Z. Ye X, et al. Among authors: chen y. PLoS Pathog. 2019 Jul 29;15(7):e1007914. doi: 10.1371/journal.ppat.1007914. eCollection 2019 Jul. PLoS Pathog. 2019. PMID: 31356650 Free PMC article.
Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells.
Chen H, Chen Y, Deng M, John S, Gui X, Kansagra A, Chen W, Kim J, Lewis C, Wu G, Xie J, Zhang L, Huang R, Liu X, Arase H, Huang Y, Yu H, Luo W, Xia N, Zhang N, An Z, Zhang CC. Chen H, et al. Among authors: chen w, chen y. J Immunother Cancer. 2020 Aug;8(2):e000515. doi: 10.1136/jitc-2019-000515. J Immunother Cancer. 2020. PMID: 32771992 Free PMC article.
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