Schmidtchen A - Search Results

1

SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade.

Samsudin F, Raghuvamsi P, Petruk G, Puthia M, Petrlova J, MacAry P, Anand GS, Bond PJ, Schmidtchen A. Samsudin F, et al. Among authors: schmidtchen a. J Mol Cell Biol. 2023 Feb 7;14(9):mjac058. doi: 10.1093/jmcb/mjac058. J Mol Cell Biol. 2023. PMID: 36240490 Free PMC article.

2

Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism.

Petrlova J, Hansen FC, van der Plas MJA, Huber RG, Mörgelin M, Malmsten M, Bond PJ, Schmidtchen A. Petrlova J, et al. Among authors: schmidtchen a. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4213-E4222. doi: 10.1073/pnas.1619609114. Epub 2017 May 4. Proc Natl Acad Sci U S A. 2017. PMID: 28473418 Free PMC article.

3

Thrombin-derived host defence peptide modulates neutrophil rolling and migration in vitro and functional response in vivo.

Lim CH, Puthia M, Butrym M, Tay HM, Lee MZY, Hou HW, Schmidtchen A. Lim CH, et al. Among authors: schmidtchen a. Sci Rep. 2017 Sep 11;7(1):11201. doi: 10.1038/s41598-017-11464-x. Sci Rep. 2017. PMID: 28894159 Free PMC article.

4

Proteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo.

Saravanan R, Adav SS, Choong YK, van der Plas MJA, Petrlova J, Kjellström S, Sze SK, Schmidtchen A. Saravanan R, et al. Among authors: schmidtchen a. Sci Rep. 2017 Oct 13;7(1):13136. doi: 10.1038/s41598-017-13197-3. Sci Rep. 2017. PMID: 29030565 Free PMC article.

5

A Thermodynamic Funnel Drives Bacterial Lipopolysaccharide Transfer in the TLR4 Pathway.

Huber RG, Berglund NA, Kargas V, Marzinek JK, Holdbrook DA, Khalid S, Piggot TJ, Schmidtchen A, Bond PJ. Huber RG, et al. Among authors: schmidtchen a. Structure. 2018 Aug 7;26(8):1151-1161.e4. doi: 10.1016/j.str.2018.04.007. Epub 2018 May 17. Structure. 2018. PMID: 29779787 Free article.

6

Influence of pH on the activity of thrombin-derived antimicrobial peptides.

Holdbrook DA, Singh S, Choong YK, Petrlova J, Malmsten M, Bond PJ, Verma NK, Schmidtchen A, Saravanan R. Holdbrook DA, et al. Among authors: schmidtchen a. Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2374-2384. doi: 10.1016/j.bbamem.2018.06.002. Epub 2018 Jun 6. Biochim Biophys Acta Biomembr. 2018. PMID: 29885294 Free article.

7

Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides.

Saravanan R, Holdbrook DA, Petrlova J, Singh S, Berglund NA, Choong YK, Kjellström S, Bond PJ, Malmsten M, Schmidtchen A. Saravanan R, et al. Among authors: schmidtchen a. Nat Commun. 2018 Jul 17;9(1):2762. doi: 10.1038/s41467-018-05242-0. Nat Commun. 2018. PMID: 30018388 Free PMC article.

8

A novel derivative of the fungal antimicrobial peptide plectasin is active against Mycobacterium tuberculosis.

Tenland E, Krishnan N, Rönnholm A, Kalsum S, Puthia M, Mörgelin M, Davoudi M, Otrocka M, Alaridah N, Glegola-Madejska I, Sturegård E, Schmidtchen A, Lerm M, Robertson BD, Godaly G. Tenland E, et al. Among authors: schmidtchen a. Tuberculosis (Edinb). 2018 Dec;113:231-238. doi: 10.1016/j.tube.2018.10.008. Epub 2018 Oct 30. Tuberculosis (Edinb). 2018. PMID: 30514507 Free PMC article.

9

Multiscale modeling of innate immune receptors: Endotoxin recognition and regulation by host defense peptides.

Holdbrook DA, Huber RG, Marzinek JK, Stubbusch A, Schmidtchen A, Bond PJ. Holdbrook DA, et al. Among authors: schmidtchen a. Pharmacol Res. 2019 Sep;147:104372. doi: 10.1016/j.phrs.2019.104372. Epub 2019 Jul 24. Pharmacol Res. 2019. PMID: 31351116 Review.

10

A dual-action peptide-containing hydrogel targets wound infection and inflammation.

Puthia M, Butrym M, Petrlova J, Strömdahl AC, Andersson MÅ, Kjellström S, Schmidtchen A. Puthia M, et al. Among authors: schmidtchen a. Sci Transl Med. 2020 Jan 1;12(524):eaax6601. doi: 10.1126/scitranslmed.aax6601. Sci Transl Med. 2020. PMID: 31894104

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