Derksen NIL - Search Results

1

The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.

Brinkhaus M, Pannecoucke E, van der Kooi EJ, Bentlage AEH, Derksen NIL, Andries J, Balbino B, Sips M, Ulrichts P, Verheesen P, de Haard H, Rispens T, Savvides SN, Vidarsson G. Brinkhaus M, et al. Among authors: derksen nil. Nat Commun. 2022 Oct 14;13(1):6073. doi: 10.1038/s41467-022-33764-1. Nat Commun. 2022. PMID: 36241613 Free PMC article.

2

Detection of conformational changes in immunoglobulin G using isothermal titration calorimetry with low-molecular-weight probes.

Rispens T, Lakemond CM, Derksen NI, Aalberse RC. Rispens T, et al. Anal Biochem. 2008 Sep 15;380(2):303-9. doi: 10.1016/j.ab.2008.06.001. Epub 2008 Jun 5. Anal Biochem. 2008. PMID: 18577365

3

Enrichment of sialylated IgG by lectin fractionation does not enhance the efficacy of immunoglobulin G in a murine model of immune thrombocytopenia.

Guhr T, Bloem J, Derksen NI, Wuhrer M, Koenderman AH, Aalberse RC, Rispens T. Guhr T, et al. PLoS One. 2011;6(6):e21246. doi: 10.1371/journal.pone.0021246. Epub 2011 Jun 23. PLoS One. 2011. PMID: 21731683 Free PMC article.

4

Use of a human recombinant immunoglobulin G1 CH3 domain as a probe for detecting alternatively folded human IgG in intravenous Ig products.

Guhr T, Derksen N, Aalberse R, Rispens T. Guhr T, et al. J Pharm Sci. 2012 Mar;101(3):978-86. doi: 10.1002/jps.22828. Epub 2011 Nov 18. J Pharm Sci. 2012. PMID: 22102504

5

IgE production to α-gal is accompanied by elevated levels of specific IgG1 antibodies and low amounts of IgE to blood group B.

Rispens T, Derksen NI, Commins SP, Platts-Mills TA, Aalberse RC. Rispens T, et al. PLoS One. 2013;8(2):e55566. doi: 10.1371/journal.pone.0055566. Epub 2013 Feb 4. PLoS One. 2013. PMID: 23390540 Free PMC article.

6

Nanomolar to sub-picomolar affinity measurements of antibody-antigen interactions and protein multimerizations: fluorescence-assisted high-performance liquid chromatography.

Rispens T, Ooijevaar-de Heer P, Derksen NI, Wolbink G, van Schouwenburg PA, Kruithof S, Aalberse RC. Rispens T, et al. Anal Biochem. 2013 Jun 15;437(2):118-22. doi: 10.1016/j.ab.2013.02.027. Epub 2013 Mar 13. Anal Biochem. 2013. PMID: 23499975

7

Preventing adsorption of immunoglobulin G to solid surfaces using poloxamer 407 eliminates artifactual stimulation of neutrophils.

Kustiawan I, Derksen NI, Rispens T. Kustiawan I, et al. J Immunol Methods. 2013 Jun 28;392(1-2):49-56. doi: 10.1016/j.jim.2013.03.009. Epub 2013 Mar 29. J Immunol Methods. 2013. PMID: 23545494

8

Antibodies to IgG4 hinge can be found in rheumatoid arthritis patients during all stages of disease and may exacerbate chronic antibody-mediated inflammation.

van de Stadt LA, de Vrieze H, Derksen NI, Brouwer M, Wouters D, van Schaardenburg D, Wolbink G, Rispens T. van de Stadt LA, et al. Arthritis Rheumatol. 2014 May;66(5):1133-40. doi: 10.1002/art.38335. Arthritis Rheumatol. 2014. PMID: 24782178

9

Inactivated pepsin inhibits neutrophil activation by Fcgamma-receptor-dependent and independent stimuli.

Kustiawan I, Derksen N, Rispens T. Kustiawan I, et al. Clin Immunol. 2016 Aug;169:85-88. doi: 10.1016/j.clim.2016.06.008. Epub 2016 Jun 29. Clin Immunol. 2016. PMID: 27368805

10

Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region.

van de Bovenkamp FS, Derksen NIL, Ooijevaar-de Heer P, van Schie KA, Kruithof S, Berkowska MA, van der Schoot CE, IJspeert H, van der Burg M, Gils A, Hafkenscheid L, Toes REM, Rombouts Y, Plomp R, Wuhrer M, van Ham SM, Vidarsson G, Rispens T. van de Bovenkamp FS, et al. Among authors: derksen nil. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1901-1906. doi: 10.1073/pnas.1711720115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432186 Free PMC article.

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