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Malaria parasites utilize two essential plasma membrane fusogens for gamete fertilization.
Kumar S, Valansi C, Haile MT, Li X, Flyak K, Dwivedy A, Abatiyow BA, Leeb AS, Kennedy SY, Camargo NM, Vaughan AM, Brukman NG, Podbilewicz B, Kappe SHI. Kumar S, et al. Among authors: flyak k. Cell Mol Life Sci. 2022 Oct 14;79(11):549. doi: 10.1007/s00018-022-04583-w. Cell Mol Life Sci. 2022. PMID: 36241929 Free PMC article.
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins.
Moi D, Nishio S, Li X, Valansi C, Langleib M, Brukman NG, Flyak K, Dessimoz C, de Sanctis D, Tunyasuvunakool K, Jumper J, Graña M, Romero H, Aguilar PS, Jovine L, Podbilewicz B. Moi D, et al. Among authors: flyak k. Nat Commun. 2022 Jul 6;13(1):3880. doi: 10.1038/s41467-022-31564-1. Nat Commun. 2022. PMID: 35794124 Free PMC article.