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HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo.
Timmons A, Fray E, Kumar M, Wu F, Dai W, Bullen CK, Kim P, Hetzel C, Yang C, Beg S, Lai J, Pomerantz JL, Yukl SA, Siliciano JD, Siliciano RF. Timmons A, et al. Among authors: wu f. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15763-15771. doi: 10.1073/pnas.1916290117. Epub 2020 Jun 22. Proc Natl Acad Sci U S A. 2020. PMID: 32571938 Free PMC article.
Engaging innate immunity in HIV-1 cure strategies.
Board NL, Moskovljevic M, Wu F, Siliciano RF, Siliciano JD. Board NL, et al. Among authors: wu f. Nat Rev Immunol. 2022 Aug;22(8):499-512. doi: 10.1038/s41577-021-00649-1. Epub 2021 Nov 25. Nat Rev Immunol. 2022. PMID: 34824401 Review.
TCR-mimic bispecific antibodies to target the HIV-1 reservoir.
Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, Jenike K, Ho YC, Gabelli SB, Kinzler KW, Vogelstein B, Zhou S, Siliciano JD, Sadegh-Nasseri S, Reinherz EL, Siliciano RF. Sengupta S, et al. Among authors: wu f. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2123406119. doi: 10.1073/pnas.2123406119. Epub 2022 Apr 8. Proc Natl Acad Sci U S A. 2022. PMID: 35394875 Free PMC article.
Clonally expanded HIV-1 proviruses with 5'-leader defects can give rise to nonsuppressible residual viremia.
White JA, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, Camilo-Contreras A, Duan J, Zheng MY, Tadzong NF, Patel HB, Quiambao JMC, Rhodehouse K, Zhang H, Lai J, Beg SA, Delannoy M, Kilcrease C, Hoffmann CJ, Poulin S, Chano F, Tremblay C, Cherian J, Barditch-Crovo P, Chida N, Moore RD, Summers MF, Siliciano RF, Siliciano JD, Simonetti FR. White JA, et al. Among authors: wu f. J Clin Invest. 2023 Mar 15;133(6):e165245. doi: 10.1172/JCI165245. J Clin Invest. 2023. PMID: 36602866 Free PMC article.
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants.
Fray EJ, Wu F, Simonetti FR, Zitzmann C, Sambaturu N, Molina-Paris C, Bender AM, Liu PT, Ventura JD, Wiseman RW, O'Connor DH, Geleziunas R, Leitner T, Ribeiro RM, Perelson AS, Barouch DH, Siliciano JD, Siliciano RF. Fray EJ, et al. Among authors: wu f. Cell Host Microbe. 2023 Mar 8;31(3):356-372.e5. doi: 10.1016/j.chom.2023.01.016. Epub 2023 Feb 20. Cell Host Microbe. 2023. PMID: 36809762 Free PMC article.
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