Drewes G - Search Results

1

The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.

Arendse LB, Murithi JM, Qahash T, Pasaje CFA, Godoy LC, Dey S, Gibhard L, Ghidelli-Disse S, Drewes G, Bantscheff M, Lafuente-Monasterio MJ, Fienberg S, Wambua L, Gachuhi S, Coertzen D, van der Watt M, Reader J, Aswat AS, Erlank E, Venter N, Mittal N, Luth MR, Ottilie S, Winzeler EA, Koekemoer LL, Birkholtz LM, Niles JC, Llinás M, Fidock DA, Chibale K. Arendse LB, et al. Among authors: drewes g. Sci Transl Med. 2022 Oct 19;14(667):eabo7219. doi: 10.1126/scitranslmed.abo7219. Epub 2022 Oct 19. Sci Transl Med. 2022. PMID: 36260689 Free PMC article.

2

Pathway proteomics and chemical proteomics team up in drug discovery.

Hopf C, Bantscheff M, Drewes G. Hopf C, et al. Among authors: drewes g. Neurodegener Dis. 2007;4(2-3):270-80. doi: 10.1159/000101851. Neurodegener Dis. 2007. PMID: 17596721 Review.

3

Proteomics-based strategies in kinase drug discovery.

Bantscheff M, Hopf C, Kruse U, Drewes G. Bantscheff M, et al. Among authors: drewes g. Ernst Schering Found Symp Proc. 2007;(3):1-28. doi: 10.1007/2789_2007_060. Ernst Schering Found Symp Proc. 2007. PMID: 18512284 Review.

4

Chemical and pathway proteomics: powerful tools for oncology drug discovery and personalized health care.

Kruse U, Bantscheff M, Drewes G, Hopf C. Kruse U, et al. Among authors: drewes g. Mol Cell Proteomics. 2008 Oct;7(10):1887-901. doi: 10.1074/mcp.R800006-MCP200. Epub 2008 Aug 1. Mol Cell Proteomics. 2008. PMID: 18676365 Free article. Review.

5

Chemoproteomic approaches to drug target identification and drug profiling.

Bantscheff M, Drewes G. Bantscheff M, et al. Among authors: drewes g. Bioorg Med Chem. 2012 Mar 15;20(6):1973-8. doi: 10.1016/j.bmc.2011.11.003. Epub 2011 Nov 9. Bioorg Med Chem. 2012. PMID: 22130419 Review.

6

Mass spectrometry approaches to monitor protein-drug interactions.

Zinn N, Hopf C, Drewes G, Bantscheff M. Zinn N, et al. Among authors: drewes g. Methods. 2012 Aug;57(4):430-40. doi: 10.1016/j.ymeth.2012.05.008. Epub 2012 Jun 8. Methods. 2012. PMID: 22687620 Review.

7

Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.

Urbaniak MD, Mathieson T, Bantscheff M, Eberhard D, Grimaldi R, Miranda-Saavedra D, Wyatt P, Ferguson MA, Frearson J, Drewes G. Urbaniak MD, et al. Among authors: drewes g. ACS Chem Biol. 2012 Nov 16;7(11):1858-65. doi: 10.1021/cb300326z. Epub 2012 Aug 23. ACS Chem Biol. 2012. PMID: 22908928 Free PMC article.

8

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

Becher I, Savitski MM, Savitski MF, Hopf C, Bantscheff M, Drewes G. Becher I, et al. Among authors: drewes g. ACS Chem Biol. 2013 Mar 15;8(3):599-607. doi: 10.1021/cb3005879. Epub 2013 Jan 7. ACS Chem Biol. 2013. PMID: 23215245

9

The commonly used PI3-kinase probe LY294002 is an inhibitor of BET bromodomains.

Dittmann A, Werner T, Chung CW, Savitski MM, Fälth Savitski M, Grandi P, Hopf C, Lindon M, Neubauer G, Prinjha RK, Bantscheff M, Drewes G. Dittmann A, et al. Among authors: drewes g. ACS Chem Biol. 2014 Feb 21;9(2):495-502. doi: 10.1021/cb400789e. Epub 2013 Dec 10. ACS Chem Biol. 2014. PMID: 24533473

10

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes.

Becher I, Dittmann A, Savitski MM, Hopf C, Drewes G, Bantscheff M. Becher I, et al. Among authors: drewes g. ACS Chem Biol. 2014 Aug 15;9(8):1736-46. doi: 10.1021/cb500235n. Epub 2014 Jun 6. ACS Chem Biol. 2014. PMID: 24877719

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