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Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with major depressive disorder.
Grant CW, Wilton AR, Kaddurah-Daouk R, Skime M, Biernacka J, Mayes T, Carmody T, Wang L, Lazaridis K, Weinshilboum R, Bobo WV, Trivedi MH, Croarkin PE, Athreya AP. Grant CW, et al. Front Pharmacol. 2022 Oct 3;13:984383. doi: 10.3389/fphar.2022.984383. eCollection 2022. Front Pharmacol. 2022. PMID: 36263124 Free PMC article.
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics.
Ji Y, Hebbring S, Zhu H, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Zeng Z, Schaid D, Mrazek DA, Kaddurah-Daouk R, Weinshilboum RM. Ji Y, et al. Clin Pharmacol Ther. 2011 Jan;89(1):97-104. doi: 10.1038/clpt.2010.250. Epub 2010 Nov 24. Clin Pharmacol Ther. 2011. PMID: 21107318 Free PMC article. Clinical Trial.
Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
Abo R, Hebbring S, Ji Y, Zhu H, Zeng ZB, Batzler A, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Fridley B, Schaid D, Kamatani N, Nakamura Y, Kubo M, Mushiroda T, Kaddurah-Daouk R, Mrazek DA, Weinshilboum RM. Abo R, et al. Pharmacogenet Genomics. 2012 Apr;22(4):247-53. doi: 10.1097/FPC.0b013e32835001c9. Pharmacogenet Genomics. 2012. PMID: 22322242 Free PMC article.
TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics.
Gupta M, Neavin D, Liu D, Biernacka J, Hall-Flavin D, Bobo WV, Frye MA, Skime M, Jenkins GD, Batzler A, Kalari K, Matson W, Bhasin SS, Zhu H, Mushiroda T, Nakamura Y, Kubo M, Wang L, Kaddurah-Daouk R, Weinshilboum RM. Gupta M, et al. Mol Psychiatry. 2016 Dec;21(12):1717-1725. doi: 10.1038/mp.2016.6. Epub 2016 Feb 23. Mol Psychiatry. 2016. PMID: 26903268 Free PMC article.
Pharmacometabolomics informs Pharmacogenomics.
Neavin D, Kaddurah-Daouk R, Weinshilboum R. Neavin D, et al. Metabolomics. 2016 Jul;12(7):121. doi: 10.1007/s11306-016-1066-x. Epub 2016 Jul 1. Metabolomics. 2016. PMID: 27516730 Free PMC article.
Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
Liu D, Ray B, Neavin DR, Zhang J, Athreya AP, Biernacka JM, Bobo WV, Hall-Flavin DK, Skime MK, Zhu H, Jenkins GD, Batzler A, Kalari KR, Boakye-Agyeman F, Matson WR, Bhasin SS, Mushiroda T, Nakamura Y, Kubo M, Iyer RK, Wang L, Frye MA, Kaddurah-Daouk R, Weinshilboum RM. Liu D, et al. Transl Psychiatry. 2018 Jan 10;8(1):10. doi: 10.1038/s41398-017-0056-8. Transl Psychiatry. 2018. PMID: 29317604 Free PMC article.
201 results