Hua X - Search Results

1

Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer.

Hua X, Li Y, Pentaparthi SR, McGrail DJ, Zou R, Guo L, Shrawat A, Cirillo KM, Li Q, Bhat A, Xu M, Qi D, Singh A, McGrath F, Andrews S, Aung KL, Das J, Zhou Y, Lodi A, Mills GB, Eckhardt SG, Mendillo ML, Tiziani S, Wu E, Huang JH, Sahni N, Yi SS. Hua X, et al. Cancer Res. 2023 Jan 4;83(1):59-73. doi: 10.1158/0008-5472.CAN-20-0371. Cancer Res. 2023. PMID: 36265133 Free PMC article.

2

Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.

Li Y, Sahni N, Pancsa R, McGrail DJ, Xu J, Hua X, Coulombe-Huntington J, Ryan M, Tychhon B, Sudhakar D, Hu L, Tyers M, Jiang X, Lin SY, Babu MM, Yi S. Li Y, et al. Among authors: hua x. Cell Rep. 2017 Oct 17;21(3):798-812. doi: 10.1016/j.celrep.2017.09.071. Cell Rep. 2017. PMID: 29045845 Free PMC article.

3

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies.

Ip CKM, Ng PKS, Jeong KJ, Shao SH, Ju Z, Leonard PG, Hua X, Vellano CP, Woessner R, Sahni N, Scott KL, Mills GB. Ip CKM, et al. Among authors: hua x. Nat Commun. 2018 Nov 2;9(1):4583. doi: 10.1038/s41467-018-06949-w. Nat Commun. 2018. PMID: 30389923 Free PMC article.

4

mi-IsoNet: systems-scale microRNA landscape reveals rampant isoform-mediated gain of target interaction diversity and signaling specificity.

Guo L, Li Y, Cirillo KM, Marick RA, Su Z, Yin X, Hua X, Mills GB, Sahni N, Yi SS. Guo L, et al. Among authors: hua x. Brief Bioinform. 2021 Sep 2;22(5):bbab091. doi: 10.1093/bib/bbab091. Brief Bioinform. 2021. PMID: 33855356 Free PMC article.

5

A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance.

Yu J, Zhang Y, Fang Y, Paulo JA, Yaghoubi D, Hua X, Shipkovenska G, Toda T, Zhang Z, Gygi SP, Jia S, Li Q, Moazed D. Yu J, et al. Among authors: hua x. Cell. 2024 Sep 5;187(18):5010-5028.e24. doi: 10.1016/j.cell.2024.07.006. Epub 2024 Aug 1. Cell. 2024. PMID: 39094570 Free PMC article.

6

CHD2 Regulates Neuron-Glioma Interactions in Pediatric Glioma.

Zhang X, Duan S, Apostolou PE, Wu X, Watanabe J, Gallitto M, Barron T, Taylor KR, Woo PJ, Hua X, Zhou H, Wei HJ, McQuillan N, Kang KD, Friedman GK, Canoll PD, Chang K, Wu CC, Hashizume R, Vakoc CR, Monje M, McKhann GM 2nd, Gogos JA, Zhang Z. Zhang X, et al. Among authors: hua x. Cancer Discov. 2024 Sep 4;14(9):1732-1754. doi: 10.1158/2159-8290.CD-23-0012. Cancer Discov. 2024. PMID: 38767413

7

Epigenome Programming by H3.3K27M Mutation Creates a Dependence of Pediatric Glioma on SMARCA4.

Mo Y, Duan S, Zhang X, Hua X, Zhou H, Wei HJ, Watanabe J, McQuillan N, Su Z, Gu W, Wu CC, Vakoc CR, Hashizume R, Chang K, Zhang Z. Mo Y, et al. Among authors: hua x. Cancer Discov. 2022 Dec 2;12(12):2906-2929. doi: 10.1158/2159-8290.CD-21-1492. Cancer Discov. 2022. PMID: 36305747 Free PMC article.

8

The PCNA-Pol δ complex couples lagging strand DNA synthesis to parental histone transfer for epigenetic inheritance.

Serra-Cardona A, Hua X, McNutt SW, Zhou H, Toda T, Jia S, Chu F, Zhang Z. Serra-Cardona A, et al. Among authors: hua x. Sci Adv. 2024 Jun 7;10(23):eadn5175. doi: 10.1126/sciadv.adn5175. Epub 2024 Jun 5. Sci Adv. 2024. PMID: 38838138 Free PMC article.

9

Tumor detection by analysis of both symmetric- and hemi-methylation of plasma cell-free DNA.

Hua X, Zhou H, Wu HC, Furnari J, Kotidis CP, Rabadan R, Genkinger JM, Bruce JN, Canoll P, Santella RM, Zhang Z. Hua X, et al. Nat Commun. 2024 Jul 20;15(1):6113. doi: 10.1038/s41467-024-50471-1. Nat Commun. 2024. PMID: 39030196 Free PMC article.

10

Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements.

Li Z, Duan S, Hua X, Xu X, Li Y, Menolfi D, Zhou H, Lu C, Zha S, Goff SP, Zhang Z. Li Z, et al. Among authors: hua x. Nature. 2023 Nov;623(7987):643-651. doi: 10.1038/s41586-023-06711-3. Epub 2023 Nov 8. Nature. 2023. PMID: 37938774 Free PMC article.

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