Mantuano E - Search Results

1

The LRP1/CD91 ligands, tissue-type plasminogen activator, α₂-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling.

Mantuano E, Azmoon P, Banki MA, Gunner CB, Gonias SL. Mantuano E, et al. Sci Rep. 2022 Oct 20;12(1):17594. doi: 10.1038/s41598-022-22498-1. Sci Rep. 2022. PMID: 36266319 Free PMC article.

2

LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.

Mantuano E, Lam MS, Gonias SL. Mantuano E, et al. J Biol Chem. 2013 Nov 22;288(47):34009-34018. doi: 10.1074/jbc.M113.509133. Epub 2013 Oct 15. J Biol Chem. 2013. PMID: 24129569 Free PMC article.

3

Tissue-type plasminogen activator regulates macrophage activation and innate immunity.

Mantuano E, Azmoon P, Brifault C, Banki MA, Gilder AS, Campana WM, Gonias SL. Mantuano E, et al. Blood. 2017 Sep 14;130(11):1364-1374. doi: 10.1182/blood-2017-04-780205. Epub 2017 Jul 6. Blood. 2017. PMID: 28684538 Free PMC article.

4

Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin.

Zalfa C, Azmoon P, Mantuano E, Gonias SL. Zalfa C, et al. Among authors: mantuano e. J Leukoc Biol. 2019 Apr;105(4):729-740. doi: 10.1002/JLB.3A0818-329RRR. Epub 2019 Jan 28. J Leukoc Biol. 2019. PMID: 30690783 Free PMC article.

5

Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages.

Das L, Azmoon P, Banki MA, Mantuano E, Gonias SL. Das L, et al. Among authors: mantuano e. PLoS One. 2019 Nov 7;14(11):e0224738. doi: 10.1371/journal.pone.0224738. eCollection 2019. PLoS One. 2019. PMID: 31697716 Free PMC article.

6

A soluble derivative of PrP^C activates cell-signaling and regulates cell physiology through LRP1 and the NMDA receptor.

Mantuano E, Azmoon P, Banki MA, Lam MS, Sigurdson CJ, Gonias SL. Mantuano E, et al. J Biol Chem. 2020 Oct 9;295(41):14178-14188. doi: 10.1074/jbc.RA120.013779. Epub 2020 Aug 11. J Biol Chem. 2020. PMID: 32788217 Free PMC article.

7

A Soluble PrP^C Derivative and Membrane-Anchored PrP^C in Extracellular Vesicles Attenuate Innate Immunity by Engaging the NMDA-R/LRP1 Receptor Complex.

Mantuano E, Azmoon P, Banki MA, Sigurdson CJ, Campana WM, Gonias SL. Mantuano E, et al. J Immunol. 2022 Jan 1;208(1):85-96. doi: 10.4049/jimmunol.2100412. Epub 2021 Nov 22. J Immunol. 2022. PMID: 34810220 Free PMC article.

8

PAI1 blocks NMDA receptor-mediated effects of tissue-type plasminogen activator on cell signaling and physiology.

Gonias SL, Banki MA, Gilder AS, Azmoon P, Campana WM, Mantuano E. Gonias SL, et al. Among authors: mantuano e. J Cell Sci. 2018 Jul 26;131(14):jcs217083. doi: 10.1242/jcs.217083. J Cell Sci. 2018. PMID: 29930084 Free PMC article.

9

Cellular prion protein in human plasma-derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor-LRP1 receptor system.

Gonias SL, Banki MA, Azmoon P, Romero HK, Sigurdson CJ, Mantuano E, Campana WM. Gonias SL, et al. Among authors: mantuano e. J Biol Chem. 2022 Mar;298(3):101642. doi: 10.1016/j.jbc.2022.101642. Epub 2022 Jan 25. J Biol Chem. 2022. PMID: 35090893 Free PMC article.

10

The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres.

Gilder AS, Natali L, Van Dyk DM, Zalfa C, Banki MA, Pizzo DP, Wang H, Klemke RL, Mantuano E, Gonias SL. Gilder AS, et al. Among authors: mantuano e. Sci Rep. 2018 Feb 14;8(1):2982. doi: 10.1038/s41598-018-21358-1. Sci Rep. 2018. PMID: 29445239 Free PMC article.

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