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A stabilized CXCL9(74-103)-derived peptide selectively inhibits proliferation, adhesion and metastasis of tumor cells that express high levels of heparan sulfate.
De Zutter A, Dillemans L, Berghmans N, Noppen S, Crijns H, Verscheure P, Verhaegen J, Martens E, Vanbrabant L, Pörtner N, Schols D, Proost P, Struyf S. De Zutter A, et al. Among authors: crijns h. Int J Biol Macromol. 2022 Dec 1;222(Pt B):2808-2822. doi: 10.1016/j.ijbiomac.2022.10.060. Epub 2022 Oct 19. Int J Biol Macromol. 2022. PMID: 36272565 No abstract available.
The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors.
De Zutter A, Crijns H, Berghmans N, García-Caballero M, Vanbrabant L, Pörtner N, Vanheule V, Verscheure P, Siddiquei MM, Abu El-Asrar AM, Carmeliet P, Van Wielendaele P, De Meester I, Van Damme J, Proost P, Struyf S. De Zutter A, et al. Among authors: crijns h. Cancers (Basel). 2021 Oct 12;13(20):5090. doi: 10.3390/cancers13205090. Cancers (Basel). 2021. PMID: 34680238 Free PMC article.
Inhibition of renal fibrosis with a human CXCL9-derived glycosaminoglycan-binding peptide.
Poosti F, Soebadi MA, Crijns H, De Zutter A, Metzemaekers M, Berghmans N, Vanheule V, Albersen M, Opdenakker G, Van Damme J, Sprangers B, Proost P, Struyf S. Poosti F, et al. Among authors: crijns h. Clin Transl Immunology. 2022 Feb 2;11(2):e1370. doi: 10.1002/cti2.1370. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35140938 Free PMC article.
Neutrophils: Beneficial and Harmful Cells in Septic Arthritis.
Boff D, Crijns H, Teixeira MM, Amaral FA, Proost P. Boff D, et al. Among authors: crijns h. Int J Mol Sci. 2018 Feb 5;19(2):468. doi: 10.3390/ijms19020468. Int J Mol Sci. 2018. PMID: 29401737 Free PMC article. Review.
The Therapeutic Treatment with the GAG-Binding Chemokine Fragment CXCL9(74-103) Attenuates Neutrophilic Inflammation and Lung Dysfunction during Klebsiella pneumoniae Infection in Mice.
Boff D, Russo RC, Crijns H, de Oliveira VLS, Mattos MS, Marques PE, Menezes GB, Vieira AT, Teixeira MM, Proost P, Amaral FA. Boff D, et al. Among authors: crijns h. Int J Mol Sci. 2022 Jun 2;23(11):6246. doi: 10.3390/ijms23116246. Int J Mol Sci. 2022. PMID: 35682923 Free PMC article.
Inhibition of Drug-Induced Liver Injury in Mice Using a Positively Charged Peptide That Binds DNA.
Marques PE, Vandendriessche S, de Oliveira THC, Crijns H, Lopes ME, Blanter M, Schuermans S, Yu K, Poosti F, Vanheule V, Janssens R, Boff D, Kungl AJ, Menezes GB, Teixeira MM, Proost P. Marques PE, et al. Among authors: crijns h. Hepatol Commun. 2021 Oct;5(10):1737-1754. doi: 10.1002/hep4.1759. Epub 2021 Jul 1. Hepatol Commun. 2021. PMID: 34532999 Free PMC article.
927 results