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253 results

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Page 1
Consensus molecular subtype transition during progression of colorectal cancer.
van de Weerd S, Torang A, Zwager LW, Koelink PJ, Koster J, Bastiaansen BA, Lammers V, Longobardi C, Roodhart JM, van Krieken JH, Farina Sarasqueta A, Dekker E, Medema JP. van de Weerd S, et al. Among authors: medema jp. J Pathol. 2023 Nov;261(3):298-308. doi: 10.1002/path.6176. Epub 2023 Sep 8. J Pathol. 2023. PMID: 37681286
Benefit of adjuvant chemotherapy on recurrence free survival per consensus molecular subtype in stage III colon cancer.
van de Weerd S, Torang A, van den Berg I, Lammers V, van den Bergh S, Brouwer N, Nagtegaal ID, Koopman M, Vink GR, van der Baan FH, van Krieken H, Koster J, Ijzermans JN, Roodhart JML, Medema JP. van de Weerd S, et al. Among authors: medema jp. Int J Cancer. 2025 Jan 15;156(2):456-466. doi: 10.1002/ijc.35120. Epub 2024 Aug 8. Int J Cancer. 2025. PMID: 39115332 Free PMC article.
Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer.
Buikhuisen JY, Gomez Barila PM, Cameron K, Suijkerbuijk SJE, Lieftink C, di Franco S, Krotenberg Garcia A, Uceda Castro R, Lenos KJ, Nijman LE, Torang A, Longobardi C, de Jong JH, Dekker D, Stassi G, Vermeulen L, Beijersbergen RL, van Rheenen J, Huveneers S, Medema JP. Buikhuisen JY, et al. Among authors: medema jp. J Exp Clin Cancer Res. 2023 Mar 3;42(1):56. doi: 10.1186/s13046-023-02600-9. J Exp Clin Cancer Res. 2023. PMID: 36869386 Free PMC article.
Transcriptome-based classification to predict FOLFIRINOX response in a real-world metastatic pancreatic cancer cohort.
Lansbergen MF, Dings MPG, Manoukian P, Fariña A, Waasdorp C, Hooijer GKJ, Verheij J, Koster J, Zwijnenburg DA, Wilmink JW, Medema JP, Dijk F, van Laarhoven HWM, Bijlsma MF. Lansbergen MF, et al. Among authors: medema jp. Transl Res. 2024 Nov;273:137-147. doi: 10.1016/j.trsl.2024.08.002. Epub 2024 Aug 21. Transl Res. 2024. PMID: 39154856 Free article.
The pluripotency factor NANOG contributes to mesenchymal plasticity and is predictive for outcome in esophageal adenocarcinoma.
van der Zalm AP, Dings MPG, Manoukian P, Boersma H, Janssen R, Bailey P, Koster J, Zwijnenburg D, Volckmann R, Bootsma S, Waasdorp C, van Mourik M, Blangé D, van den Ende T, Oyarce CI, Derks S, Creemers A, Ebbing EA, Hooijer GK, Meijer SL, van Berge Henegouwen MI, Medema JP, van Laarhoven HWM, Bijlsma MF. van der Zalm AP, et al. Among authors: medema jp. Commun Med (Lond). 2024 May 17;4(1):89. doi: 10.1038/s43856-024-00512-z. Commun Med (Lond). 2024. PMID: 38760583 Free PMC article.
Estrogen-related receptor alpha drives mitochondrial biogenesis and resistance to neoadjuvant chemoradiation in esophageal cancer.
Dings MPG, van der Zalm AP, Bootsma S, van Maanen TFJ, Waasdorp C, van den Ende T, Liu D, Bailey P, Koster J, Zwijnenburg DA, Spek CA, Klomp JPG, Oubrie A, Hooijer GKJ, Meijer SL, van Berge Henegouwen MI, Hulshof MC, Bergman J, Oyarce C, Medema JP, van Laarhoven HWM, Bijlsma MF. Dings MPG, et al. Among authors: medema jp. Cell Rep Med. 2022 Nov 15;3(11):100802. doi: 10.1016/j.xcrm.2022.100802. Epub 2022 Nov 4. Cell Rep Med. 2022. PMID: 36334593 Free PMC article.
Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases.
Bootsma S, Dings MPG, Kesselaar J, Helderman RFCPA, van Megesen K, Constantinides A, Moreno LF, Stelloo E, Scutigliani EM, Bokan B, Torang A, van Hooff SR, Zwijnenburg DA, Wouters VM, van de Vlasakker VCJ, Galanos LJK, Nijman LE, Logiantara A, Veenstra VL, Schlingemann S, van Piggelen S, van der Wel N, Krawczyk PM, Platteeuw JJ, Tuynman JB, de Hingh IH, Klomp JPG, Oubrie A, Snaebjornsson P, Medema JP, Oei AL, Kranenburg O, Elbers CC, Lenos KJ, Vermeulen L, Bijlsma MF. Bootsma S, et al. Among authors: medema jp. Cell Rep Med. 2024 May 21;5(5):101523. doi: 10.1016/j.xcrm.2024.101523. Epub 2024 Apr 25. Cell Rep Med. 2024. PMID: 38670098 Free PMC article.
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Ramadan R, Wouters VM, van Neerven SM, de Groot NE, Garcia TM, Muncan V, Franklin OD, Battle M, Carlson KS, Leach J, Sansom OJ, Boulard O, Chamaillard M, Vermeulen L, Medema JP, Huels DJ. Ramadan R, et al. Among authors: medema jp. Biol Open. 2022 Dec 15;11(12):bio059544. doi: 10.1242/bio.059544. Epub 2022 Nov 23. Biol Open. 2022. PMID: 36350252 Free PMC article.
253 results