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Molecular mechanism of α-synuclein aggregation on lipid membranes revealed.
Dear AJ, Teng X, Ball SR, Lewin J, Horne RI, Clow D, Stevenson A, Harper N, Yahya K, Yang X, Brewerton SC, Thomson J, Michaels TCT, Linse S, Knowles TPJ, Habchi J, Meisl G. Dear AJ, et al. Among authors: michaels tct. Chem Sci. 2024 Apr 22;15(19):7229-7242. doi: 10.1039/d3sc05661a. eCollection 2024 May 15. Chem Sci. 2024. PMID: 38756798 Free PMC article.
A solid beta-sheet structure is formed at the surface of FUS droplets during aging.
Emmanouilidis L, Bartalucci E, Kan Y, Ijavi M, Pérez ME, Afanasyev P, Boehringer D, Zehnder J, Parekh SH, Bonn M, Michaels TCT, Wiegand T, Allain FH. Emmanouilidis L, et al. Among authors: michaels tct. Nat Chem Biol. 2024 Aug;20(8):1044-1052. doi: 10.1038/s41589-024-01573-w. Epub 2024 Mar 11. Nat Chem Biol. 2024. PMID: 38467846 Free PMC article.
Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites.
Curk S, Krausser J, Meisl G, Frenkel D, Linse S, Michaels TCT, Knowles TPJ, Šarić A. Curk S, et al. Among authors: michaels tct. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2220075121. doi: 10.1073/pnas.2220075121. Epub 2024 Feb 9. Proc Natl Acad Sci U S A. 2024. PMID: 38335256 Free PMC article.
149 results