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Page 1
Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation.
Chandra B, Michmerhuizen NL, Shirnekhi HK, Tripathi S, Pioso BJ, Baggett DW, Mitrea DM, Iacobucci I, White MR, Chen J, Park CG, Wu H, Pounds S, Medyukhina A, Khairy K, Gao Q, Qu C, Abdelhamed S, Gorman SD, Bawa S, Maslanka C, Kinger S, Dogra P, Ferrolino MC, Di Giacomo D, Mecucci C, Klco JM, Mullighan CG, Kriwacki RW. Chandra B, et al. Among authors: baggett dw. Cancer Discov. 2022 Apr 1;12(4):1152-1169. doi: 10.1158/2159-8290.CD-21-0674. Cancer Discov. 2022. PMID: 34903620 Free PMC article.
Defining the condensate landscape of fusion oncoproteins.
Tripathi S, Shirnekhi HK, Gorman SD, Chandra B, Baggett DW, Park CG, Somjee R, Lang B, Hosseini SMH, Pioso BJ, Li Y, Iacobucci I, Gao Q, Edmonson MN, Rice SV, Zhou X, Bollinger J, Mitrea DM, White MR, McGrail DJ, Jarosz DF, Yi SS, Babu MM, Mullighan CG, Zhang J, Sahni N, Kriwacki RW. Tripathi S, et al. Among authors: baggett dw. Nat Commun. 2023 Sep 28;14(1):6008. doi: 10.1038/s41467-023-41655-2. Nat Commun. 2023. PMID: 37770423 Free PMC article.
Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia.
Jin Q, Harris E, Myers JA, Mehmood R, Cotton A, Shirnekhi HK, Baggett DW, Wen JQ, Schild AB, Bhansali RS, Klein J, Narina S, Pieters T, Yoshimi A, Pruett-Miller SM, Kriwacki R, Abdel-Wahab O, Malinge S, Ntziachristos P, Obeng EA, Crispino JD. Jin Q, et al. Among authors: baggett dw. Blood. 2024 Dec 5;144(23):2417-2431. doi: 10.1182/blood.2024024281. Blood. 2024. PMID: 39316649 Free PMC article.
The Rational Discovery of a Tau Aggregation Inhibitor.
Baggett DW, Nath A. Baggett DW, et al. Biochemistry. 2018 Oct 23;57(42):6099-6107. doi: 10.1021/acs.biochem.8b00581. Epub 2018 Oct 5. Biochemistry. 2018. PMID: 30247897 Free PMC article.
16 results