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Page 1
Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.
Li Y, Sahni N, Pancsa R, McGrail DJ, Xu J, Hua X, Coulombe-Huntington J, Ryan M, Tychhon B, Sudhakar D, Hu L, Tyers M, Jiang X, Lin SY, Babu MM, Yi S. Li Y, et al. Among authors: tyers m. Cell Rep. 2017 Oct 17;21(3):798-812. doi: 10.1016/j.celrep.2017.09.071. Cell Rep. 2017. PMID: 29045845 Free PMC article.
The BioGRID interaction database: 2019 update.
Oughtred R, Stark C, Breitkreutz BJ, Rust J, Boucher L, Chang C, Kolas N, O'Donnell L, Leung G, McAdam R, Zhang F, Dolma S, Willems A, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M. Oughtred R, et al. Among authors: tyers m. Nucleic Acids Res. 2019 Jan 8;47(D1):D529-D541. doi: 10.1093/nar/gky1079. Nucleic Acids Res. 2019. PMID: 30476227 Free PMC article.
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.
Baccelli I, Gareau Y, Lehnertz B, Gingras S, Spinella JF, Corneau S, Mayotte N, Girard S, Frechette M, Blouin-Chagnon V, Leveillé K, Boivin I, MacRae T, Krosl J, Thiollier C, Lavallée VP, Kanshin E, Bertomeu T, Coulombe-Huntington J, St-Denis C, Bordeleau ME, Boucher G, Roux PP, Lemieux S, Tyers M, Thibault P, Hébert J, Marinier A, Sauvageau G. Baccelli I, et al. Among authors: tyers m. Cancer Cell. 2019 Jul 8;36(1):84-99.e8. doi: 10.1016/j.ccell.2019.06.003. Cancer Cell. 2019. PMID: 31287994 Free article.
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development.
Jacques S, van der Sloot AM, C Huard C, Coulombe-Huntington J, Tsao S, Tollis S, Bertomeu T, Culp EJ, Pallant D, Cook MA, Bonneil E, Thibault P, Wright GD, Tyers M. Jacques S, et al. Among authors: tyers m. Genetics. 2020 Apr;214(4):1103-1120. doi: 10.1534/genetics.119.302851. Epub 2020 Feb 24. Genetics. 2020. PMID: 32094149 Free PMC article.
Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells.
Benslimane Y, Bertomeu T, Coulombe-Huntington J, McQuaid M, Sánchez-Osuna M, Papadopoli D, Avizonis D, Russo MST, Huard C, Topisirovic I, Wurtele H, Tyers M, Harrington L. Benslimane Y, et al. Among authors: tyers m. Mol Cell. 2020 Sep 3;79(5):846-856.e8. doi: 10.1016/j.molcel.2020.07.010. Epub 2020 Aug 4. Mol Cell. 2020. PMID: 32755594 Free article.
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality.
Mast FD, Navare AT, van der Sloot AM, Coulombe-Huntington J, Rout MP, Baliga NS, Kaushansky A, Chait BT, Aderem A, Rice CM, Sali A, Tyers M, Aitchison JD. Mast FD, et al. Among authors: tyers m. J Cell Biol. 2020 Oct 5;219(10):e202006159. doi: 10.1083/jcb.202006159. J Cell Biol. 2020. PMID: 32785687 Free PMC article.
340 results