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The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages.
Ten Hoeve AL, Braun L, Rodriguez ME, Olivera GC, Bougdour A, Belmudes L, Couté Y, Saeij JPJ, Hakimi MA, Barragan A. Ten Hoeve AL, et al. Among authors: coute y. Cell Host Microbe. 2022 Nov 9;30(11):1570-1588.e7. doi: 10.1016/j.chom.2022.10.001. Epub 2022 Oct 28. Cell Host Microbe. 2022. PMID: 36309013 Free PMC article.
Host cell subversion by Toxoplasma GRA16, an exported dense granule protein that targets the host cell nucleus and alters gene expression.
Bougdour A, Durandau E, Brenier-Pinchart MP, Ortet P, Barakat M, Kieffer S, Curt-Varesano A, Curt-Bertini RL, Bastien O, Coute Y, Pelloux H, Hakimi MA. Bougdour A, et al. Among authors: coute y. Cell Host Microbe. 2013 Apr 17;13(4):489-500. doi: 10.1016/j.chom.2013.03.002. Cell Host Microbe. 2013. PMID: 23601110 Free article.
A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation.
Braun L, Brenier-Pinchart MP, Yogavel M, Curt-Varesano A, Curt-Bertini RL, Hussain T, Kieffer-Jaquinod S, Coute Y, Pelloux H, Tardieux I, Sharma A, Belrhali H, Bougdour A, Hakimi MA. Braun L, et al. Among authors: coute y. J Exp Med. 2013 Sep 23;210(10):2071-86. doi: 10.1084/jem.20130103. Epub 2013 Sep 16. J Exp Med. 2013. PMID: 24043761 Free PMC article.
Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ-mediated host defenses.
Gay G, Braun L, Brenier-Pinchart MP, Vollaire J, Josserand V, Bertini RL, Varesano A, Touquet B, De Bock PJ, Coute Y, Tardieux I, Bougdour A, Hakimi MA. Gay G, et al. Among authors: coute y. J Exp Med. 2016 Aug 22;213(9):1779-98. doi: 10.1084/jem.20160340. Epub 2016 Aug 8. J Exp Med. 2016. PMID: 27503074 Free PMC article.
200 results