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A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity.
Nuber S, Chung CY, Tardiff DF, Bechade PA, McCaffery TD, Shimanaka K, Choi J, Chang B, Raja W, Neves E, Burke C, Jiang X, Xu P, Khurana V, Dettmer U, Fanning S, Rhodes KJ, Selkoe DJ, Scannevin RH. Nuber S, et al. Among authors: dettmer u. Neurotherapeutics. 2022 Apr;19(3):1018-1036. doi: 10.1007/s13311-022-01199-7. Epub 2022 Apr 20. Neurotherapeutics. 2022. PMID: 35445353 Free PMC article.
Correction to: A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity.
Nuber S, Chung CY, Tardiff DF, Bechade PA, McCaffery TD, Shimanaka K, Choi J, Chang B, Raja W, Neves E, Burke C, Jiang X, Xu P, Khurana V, Dettmer U, Fanning S, Rhodes KJ, Selkoe DJ, Scannevin RH. Nuber S, et al. Among authors: dettmer u. Neurotherapeutics. 2022 Jul;19(4):1434. doi: 10.1007/s13311-022-01268-x. Neurotherapeutics. 2022. PMID: 35792968 Free PMC article. No abstract available.
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity.
Ramalingam N, Jin SX, Moors TE, Fonseca-Ornelas L, Shimanaka K, Lei S, Cam HP, Watson AH, Brontesi L, Ding L, Hacibaloglu DY, Jiang H, Choi SJ, Kanter E, Liu L, Bartels T, Nuber S, Sulzer D, Mosharov EV, Chen WV, Li S, Selkoe DJ, Dettmer U. Ramalingam N, et al. Among authors: dettmer u. NPJ Parkinsons Dis. 2023 Jan 16;9(1):4. doi: 10.1038/s41531-023-00444-w. NPJ Parkinsons Dis. 2023. PMID: 36646701 Free PMC article.
5-Nitro-1,2-benzothiazol-3-amine and N-Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α-Synuclein and Tau Aggregation.
Ramirez E, Ganegamage SK, Elbatrawy AA, Alnakhala H, Shimanaka K, Tripathi A, Min S, Rochet JC, Dettmer U, Fortin JS. Ramirez E, et al. Among authors: dettmer u. ACS Omega. 2023 May 23;8(22):20102-20115. doi: 10.1021/acsomega.3c02668. eCollection 2023 Jun 6. ACS Omega. 2023. PMID: 37305264 Free PMC article.
Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on α-Synuclein and Tau Aggregation.
Ramirez E, Ganegamage SK, Min S, Patel H, Ogunware A, Plascencia-Villa G, Alnakhala H, Shimanaka K, Tripathi A, Wang KW, Zhu X, Rochet JC, Kuo MH, Counts SE, Perry G, Dettmer U, Lasagna-Reeves CA, Fortin JS. Ramirez E, et al. Among authors: dettmer u. ACS Chem Neurosci. 2023 Nov 1;14(21):3913-3927. doi: 10.1021/acschemneuro.3c00464. Epub 2023 Oct 11. ACS Chem Neurosci. 2023. PMID: 37818657 Free PMC article.
61 results