Kim WK - Search Results

1

Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis.

Hiroto A, Kim WK, Pineda A, He Y, Lee DH, Le V, Olson AW, Aldahl J, Nenninger CH, Buckley AJ, Xiao GQ, Geradts J, Sun Z. Hiroto A, et al. Among authors: kim wk. Nat Commun. 2022 Nov 2;13(1):6552. doi: 10.1038/s41467-022-34282-w. Nat Commun. 2022. PMID: 36323713 Free PMC article.

2

A pivotal role of androgen signaling in Notch-responsive cells in prostate development, maturation, and regeneration.

Aldahl J, Yu EJ, He Y, Hooker E, Wong M, Le V, Olson A, Lee DH, Kim WK, Murtaugh CL, Cunha GR, Sun Z. Aldahl J, et al. Among authors: kim wk. Differentiation. 2019 May-Jun;107:1-10. doi: 10.1016/j.diff.2019.03.002. Epub 2019 Mar 22. Differentiation. 2019. PMID: 30927641 Free PMC article.

3

Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate.

He Y, Johnson DT, Yang JS, Wu H, You S, Yoon J, Lee DH, Kim WK, Aldahl J, Le V, Hooker E, Yu EJ, Geradts J, Cardiff RD, Sun Z. He Y, et al. Among authors: kim wk. Oncogene. 2019 Sep;38(38):6507-6520. doi: 10.1038/s41388-019-0901-8. Epub 2019 Jul 29. Oncogene. 2019. PMID: 31358900 Free PMC article.

4

The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression.

Olson A, Le V, Aldahl J, Yu EJ, Hooker E, He Y, Lee DH, Kim WK, Cardiff RD, Geradts J, Sun Z. Olson A, et al. Among authors: kim wk. PLoS Genet. 2019 Oct 28;15(10):e1008451. doi: 10.1371/journal.pgen.1008451. eCollection 2019 Oct. PLoS Genet. 2019. PMID: 31658259 Free PMC article.

5

Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin-mediated prostatic tumorigenesis.

Aldahl J, Mi J, Pineda A, Kim WK, Olson A, Hooker E, He Y, Yu EJ, Le V, Lee DH, Geradts J, Sun Z. Aldahl J, et al. Among authors: kim wk. J Biol Chem. 2020 Jan 10;295(2):631-644. doi: 10.1074/jbc.RA119.011137. Epub 2019 Dec 9. J Biol Chem. 2020. PMID: 31819003 Free PMC article.

6

Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration.

Le V, He Y, Aldahl J, Hooker E, Yu EJ, Olson A, Kim WK, Lee DH, Wong M, Sheng R, Mi J, Geradts J, Cunha GR, Sun Z. Le V, et al. Among authors: kim wk. PLoS Genet. 2020 Jan 13;16(1):e1008588. doi: 10.1371/journal.pgen.1008588. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31929563 Free PMC article.

7

Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis.

He Y, Mi J, Olson A, Aldahl J, Hooker E, Yu EJ, Le V, Lee DH, Kim WK, Robins DM, Geradts J, Sun Z. He Y, et al. Among authors: kim wk. Oncogene. 2020 Apr;39(16):3276-3291. doi: 10.1038/s41388-020-1214-7. Epub 2020 Feb 24. Oncogene. 2020. PMID: 32089544 Free PMC article.

8

Androgen action in cell fate and communication during prostate development at single-cell resolution.

Lee DH, Olson AW, Wang J, Kim WK, Mi J, Zeng H, Le V, Aldahl J, Hiroto A, Wu X, Sun Z. Lee DH, et al. Among authors: kim wk. Development. 2021 Jan 11;148(1):dev196048. doi: 10.1242/dev.196048. Development. 2021. PMID: 33318148 Free PMC article.

9

Stromal androgen and hedgehog signaling regulates stem cell niches in pubertal prostate development.

Olson AW, Le V, Wang J, Hiroto A, Kim WK, Lee DH, Aldahl J, Wu X, Kim M, Cunha GR, You S, Sun Z. Olson AW, et al. Among authors: kim wk, kim m. Development. 2021 Oct 1;148(19):dev199738. doi: 10.1242/dev.199738. Epub 2021 Sep 23. Development. 2021. PMID: 34427305 Free PMC article.

10

Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes.

Kim WK, Olson AW, Mi J, Wang J, Lee DH, Le V, Hiroto A, Aldahl J, Nenninger CH, Buckley AJ, Cardiff R, You S, Sun Z. Kim WK, et al. Nat Commun. 2022 Jul 28;13(1):4364. doi: 10.1038/s41467-022-32119-0. Nat Commun. 2022. PMID: 35902588 Free PMC article.

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