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NKTR-255, a novel polymer-conjugated rhIL-15 with potent antitumor efficacy.
Miyazaki T, Maiti M, Hennessy M, Chang T, Kuo P, Addepalli M, Obalapur P, Sheibani S, Wilczek J, Pena R, Quach P, Cetz J, Moffett A, Tang Y, Kirk P, Huang J, Sheng D, Zhang P, Rubas W, Madakamutil L, Kivimäe S, Zalevsky J. Miyazaki T, et al. J Immunother Cancer. 2021 May;9(5):e002024. doi: 10.1136/jitc-2020-002024. J Immunother Cancer. 2021. PMID: 34001523 Free PMC article.
The regulatory T cell-selective interleukin-2 receptor agonist rezpegaldesleukin in the treatment of inflammatory skin diseases: two randomized, double-blind, placebo-controlled phase 1b trials.
Silverberg JI, Rosmarin D, Chovatiya R, Bieber T, Schleicher S, Beck L, Gooderham M, Chaudhry S, Fanton C, Yu D, Levy J, Liu Y, Miyazaki T, Tagliaferri M, Schmitz C, Nirula A, Kotzin B, Zalevsky J. Silverberg JI, et al. Among authors: miyazaki t. Nat Commun. 2024 Oct 25;15(1):9230. doi: 10.1038/s41467-024-53384-1. Nat Commun. 2024. PMID: 39455575 Free PMC article. Clinical Trial.
NKTR-181: A Novel Mu-Opioid Analgesic with Inherently Low Abuse Potential.
Miyazaki T, Choi IY, Rubas W, Anand NK, Ali C, Evans J, Gursahani H, Hennessy M, Kim G, McWeeney D, Pfeiffer J, Quach P, Gauvin D, Riley TA, Riggs JA, Gogas K, Zalevsky J, Doberstein SK. Miyazaki T, et al. J Pharmacol Exp Ther. 2017 Oct;363(1):104-113. doi: 10.1124/jpet.117.243030. Epub 2017 Aug 4. J Pharmacol Exp Ther. 2017. PMID: 28778859
In vivo and in vitro Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development.
Lee AS, Tiwari S, Bishop I, Matossian V, Romaneschi N, Miyazaki T, VanderVeen L, Zalevsky J, DeFea K, Cahill CM, Walwyn WM. Lee AS, et al. Among authors: miyazaki t. Front Pain Res (Lausanne). 2021 Aug 23;2:695962. doi: 10.3389/fpain.2021.695962. eCollection 2021. Front Pain Res (Lausanne). 2021. PMID: 35295409 Free PMC article.
Preclinical Assessment of the Analgesic Pharmacology of NKTR-181 in Rodents.
Kopruszinski CM, Swiokla J, Lee YS, Navratilova E, VanderVeen L, Yang M, Liu Y, Miyazaki T, Schmidt WK, Zalevsky J, Porreca F. Kopruszinski CM, et al. Among authors: miyazaki t. Cell Mol Neurobiol. 2021 Jul;41(5):949-960. doi: 10.1007/s10571-020-00816-3. Epub 2020 Feb 27. Cell Mol Neurobiol. 2021. PMID: 32107752
Baseline inflammatory status affects the prognostic impact of statins in patients with peripheral arterial disease.
Jujo K, Ueshima D, Abe T, Shimazaki K, Fujimoto Y, Tanaka T, Murata T, Miyazaki T, Matsumoto M, Tokuyama H, Shimura T, Funada R, Murata N, Higashitani M; Toma-Code Registry Investigators. Jujo K, et al. Among authors: miyazaki t. Am Heart J Plus. 2024 Oct 30;47:100481. doi: 10.1016/j.ahjo.2024.100481. eCollection 2024 Nov. Am Heart J Plus. 2024. PMID: 39559793 Free PMC article.
4,284 results