Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Scherer S, Oberle SG, Kanev K, Gerullis AK, Wu M, de Almeida GP, Puleston DJ, Baixauli F, Aly L, Greco A, Nizharadze T, Becker NB, Hoesslin MV, Donhauser LV, Berner J, Chu T, McNamara HA, Esencan Z, Roelli P, Wurmser C, Kleiter I, Vehreschild MJGT, Mayer CA, Knolle P, Klingenspor M, Fumagalli V, Iannacone M, Prlic M, Korn T, Pearce EL, Höfer T, Schulz AM, Zehn D.
Scherer S, et al. Among authors: wurmser c.
Nat Immunol. 2023 Mar;24(3):501-515. doi: 10.1038/s41590-023-01436-x. Epub 2023 Feb 16.
Nat Immunol. 2023.
PMID: 36797499