Beumer J - Search Results

1

Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models.

Beumer J, Bauzá-Martinez J, Veth TS, Geurts V, Boot C, Gilliam-Vigh H, Poulsen SS, Knop FK, Wu W, Clevers H. Beumer J, et al. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2212057119. doi: 10.1073/pnas.2212057119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343264 Free PMC article.

2

Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele.

Basak O, van de Born M, Korving J, Beumer J, van der Elst S, van Es JH, Clevers H. Basak O, et al. Among authors: beumer j. EMBO J. 2014 Sep 17;33(18):2057-68. doi: 10.15252/embj.201488017. Epub 2014 Aug 4. EMBO J. 2014. PMID: 25092767 Free PMC article.

3

Regulation and plasticity of intestinal stem cells during homeostasis and regeneration.

Beumer J, Clevers H. Beumer J, et al. Development. 2016 Oct 15;143(20):3639-3649. doi: 10.1242/dev.133132. Development. 2016. PMID: 27802133 Review.

4

Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells.

Basak O, Beumer J, Wiebrands K, Seno H, van Oudenaarden A, Clevers H. Basak O, et al. Among authors: beumer j. Cell Stem Cell. 2017 Feb 2;20(2):177-190.e4. doi: 10.1016/j.stem.2016.11.001. Epub 2016 Dec 8. Cell Stem Cell. 2017. PMID: 27939219 Free article.

5

How the Gut Feels, Smells, and Talks.

Beumer J, Clevers H. Beumer J, et al. Cell. 2017 Jun 29;170(1):10-11. doi: 10.1016/j.cell.2017.06.023. Cell. 2017. PMID: 28666112 Free article.

6

Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient.

Beumer J, Artegiani B, Post Y, Reimann F, Gribble F, Nguyen TN, Zeng H, Van den Born M, Van Es JH, Clevers H. Beumer J, et al. Nat Cell Biol. 2018 Aug;20(8):909-916. doi: 10.1038/s41556-018-0143-y. Epub 2018 Jul 23. Nat Cell Biol. 2018. PMID: 30038251 Free PMC article.

7

ROCKin' Intestinal Cell Fate: A Potential Avenue to Improve Glucose Sensitivity.

Beumer J, Clevers H. Beumer J, et al. Gastroenterology. 2018 Oct;155(4):974-976. doi: 10.1053/j.gastro.2018.09.005. Epub 2018 Sep 8. Gastroenterology. 2018. PMID: 30201364 No abstract available.

8

Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping.

Gehart H, van Es JH, Hamer K, Beumer J, Kretzschmar K, Dekkers JF, Rios A, Clevers H. Gehart H, et al. Among authors: beumer j. Cell. 2019 Feb 21;176(5):1158-1173.e16. doi: 10.1016/j.cell.2018.12.029. Epub 2019 Jan 31. Cell. 2019. PMID: 30712869 Free article.

9

Snake Venom Gland Organoids.

Post Y, Puschhof J, Beumer J, Kerkkamp HM, de Bakker MAG, Slagboom J, de Barbanson B, Wevers NR, Spijkers XM, Olivier T, Kazandjian TD, Ainsworth S, Iglesias CL, van de Wetering WJ, Heinz MC, van Ineveld RL, van Kleef RGDM, Begthel H, Korving J, Bar-Ephraim YE, Getreuer W, Rios AC, Westerink RHS, Snippert HJG, van Oudenaarden A, Peters PJ, Vonk FJ, Kool J, Richardson MK, Casewell NR, Clevers H. Post Y, et al. Among authors: beumer j. Cell. 2020 Jan 23;180(2):233-247.e21. doi: 10.1016/j.cell.2019.11.038. Cell. 2020. PMID: 31978343 Free article.

10

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing.

Artegiani B, Hendriks D, Beumer J, Kok R, Zheng X, Joore I, Chuva de Sousa Lopes S, van Zon J, Tans S, Clevers H. Artegiani B, et al. Among authors: beumer j. Nat Cell Biol. 2020 Mar;22(3):321-331. doi: 10.1038/s41556-020-0472-5. Epub 2020 Mar 2. Nat Cell Biol. 2020. PMID: 32123335

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