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Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype.
Wesseler F, Lohmann S, Riege D, Halver J, Roth A, Pichlo C, Weber S, Takamiya M, Müller E, Ketzel J, Flegel J, Gihring A, Rastegar S, Bertrand J, Baumann U, Knippschild U, Peifer C, Sievers S, Waldmann H, Schade D. Wesseler F, et al. Among authors: lohmann s. J Med Chem. 2022 Nov 24;65(22):15263-15281. doi: 10.1021/acs.jmedchem.2c01199. Epub 2022 Nov 8. J Med Chem. 2022. PMID: 36346705
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion.
Tuz AA, Ghosh S, Karsch L, Ttoouli D, Sata SP, Ulusoy Ö, Kraus A, Hoerenbaum N, Wolf JN, Lohmann S, Zwirnlein F, Kaygusuz V, Lakovic V, Tummes HL, Beer A, Gallert M, Thiebes S, Qefalia A, Cibir Z, Antler M, Korste S, Haj Yehia E, Michel L, Rassaf T, Kaltwasser B, Abdelrahman H, Mohamud Yusuf A, Wang C, Yin D, Haeusler L, Lueong S, Richter M, Engel DR, Stenzel M, Soehnlein O, Frank B, Solo-Nomenjanahary M, Ho-Tin-Noé B, Siveke JT, Totzeck M, Hoffmann D, Grüneboom A, Hagemann N, Hasenberg A, Desilles JP, Mazighi M, Sickmann A, Chen J, Hermann DM, Gunzer M, Singh V. Tuz AA, et al. Among authors: lohmann s. Nat Cardiovasc Res. 2024 May;3(5):525-540. doi: 10.1038/s44161-024-00462-8. Epub 2024 Apr 23. Nat Cardiovasc Res. 2024. PMID: 39195931 Free PMC article.
Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties.
Sela T, Mansø M, Siegel M, Marban-Doran C, Ducret A, Niewöhner J, Ravn J, Martin RE, Sommer A, Lohmann S, Krippendorff BF, Ladefoged M, Indlekofer A, Quaiser T, Bueddefeld F, Koller E, Mohamed MY, Oelschlaegel T, Gothelf KV, Hofer K, Schumacher FF. Sela T, et al. Among authors: lohmann s. Bioconjug Chem. 2023 Nov 15;34(11):2096-2111. doi: 10.1021/acs.bioconjchem.3c00393. Epub 2023 Nov 2. Bioconjug Chem. 2023. PMID: 37916986
Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity.
Stokowska A, Aswendt M, Zucha D, Lohmann S, Wieters F, Morán Suarez J, Atkins AL, Li Y, Miteva M, Lewin J, Wiedermann D, Diedenhofen M, Torinsson Naluai Å, Abaffy P, Valihrach L, Kubista M, Hoehn M, Pekny M, Pekna M. Stokowska A, et al. Among authors: lohmann s. J Clin Invest. 2023 May 15;133(10):e162253. doi: 10.1172/JCI162253. J Clin Invest. 2023. PMID: 36995772 Free PMC article.
178 results