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A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between metastasis and NAD+ metabolism.
Maric T, Bazhin A, Khodakivskyi P, Mikhaylov G, Solodnikova E, Yevtodiyenko A, Giordano Attianese GMP, Coukos G, Irving M, Joffraud M, Cantó C, Goun E. Maric T, et al. Among authors: irving m. Biosens Bioelectron. 2023 Jan 15;220:114826. doi: 10.1016/j.bios.2022.114826. Epub 2022 Oct 29. Biosens Bioelectron. 2023. PMID: 36371959
Targeting the tumor vasculature to enhance T cell activity.
Lanitis E, Irving M, Coukos G. Lanitis E, et al. Among authors: irving m. Curr Opin Immunol. 2015 Apr;33:55-63. doi: 10.1016/j.coi.2015.01.011. Epub 2015 Feb 6. Curr Opin Immunol. 2015. PMID: 25665467 Free PMC article. Review.
1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).
Röhrig UF, Majjigapu SR, Caldelari D, Dilek N, Reichenbach P, Ascencao K, Irving M, Coukos G, Vogel P, Zoete V, Michielin O. Röhrig UF, et al. Among authors: irving m. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4330-3. doi: 10.1016/j.bmcl.2016.07.031. Epub 2016 Jul 16. Bioorg Med Chem Lett. 2016. PMID: 27469130
Safety and Tolerability of Adoptive Cell Therapy in Cancer.
Wolf B, Zimmermann S, Arber C, Irving M, Trueb L, Coukos G. Wolf B, et al. Among authors: irving m. Drug Saf. 2019 Feb;42(2):315-334. doi: 10.1007/s40264-018-0779-3. Drug Saf. 2019. PMID: 30649750 Review.
Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.
Vigano S, Alatzoglou D, Irving M, Ménétrier-Caux C, Caux C, Romero P, Coukos G. Vigano S, et al. Among authors: irving m. Front Immunol. 2019 Jun 6;10:925. doi: 10.3389/fimmu.2019.00925. eCollection 2019. Front Immunol. 2019. PMID: 31244820 Free PMC article. Review.
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy.
Giordano-Attianese G, Gainza P, Gray-Gaillard E, Cribioli E, Shui S, Kim S, Kwak MJ, Vollers S, Corria Osorio AJ, Reichenbach P, Bonet J, Oh BH, Irving M, Coukos G, Correia BE. Giordano-Attianese G, et al. Among authors: irving m. Nat Biotechnol. 2020 Apr;38(4):426-432. doi: 10.1038/s41587-019-0403-9. Epub 2020 Feb 3. Nat Biotechnol. 2020. PMID: 32015549
675 results